Autonomous LLM Execution for Bio-Activity Discovery Pipelines

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Solution Overview

Problem

Existing systems for biological discovery pipelines are inefficient, rigid, and require user-defined configurations, leading to slow and inaccurate execution of complex workflows.

Innovation Solution

An AI tech-bio system utilizing a language machine learning model as an autonomous reasoner to navigate and execute multiple layers of a bio-activity discovery pipeline, autonomously interacting with tech-bio exploration tools to generate and retrieve bio-activity data.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If existing systems are used to execute biological discovery pipeline workflows, then user configurations can be applied, but the execution is slow and inefficient

Engineering Contradiction:
Improveworkflow execution speedVSAvoidtime required for workflow execution
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The language machine learning model autonomously executes the bio-activity discovery pipeline workflows without requiring user configurations or manual intervention. The model self-services by understanding natural language queries, automatically selecting appropriate tools and parameters, executing workflows, and interpreting results, thereby eliminating the time-consuming manual setup and configuration steps in existing systems

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces the manual mechanical process of user configuration and workflow setup with an intelligent automated system. The language machine learning model substitutes the mechanical interaction between users and system interfaces with natural language processing, automatically translating user intent into executed workflows without manual parameter setting or tool selection

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Adaptability or versatility

If existing systems are used for biological discovery pipelines, then basic functionality is provided, but the systems are rigid and limited by user configurations

Engineering Contradiction:
Improveworkflow flexibilityVSAvoiduser configuration requirement
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The system transitions from static, pre-configured workflows to dynamic, adaptive workflows driven by natural language queries. The language machine learning model dynamically adjusts workflow parameters, tool selection, and execution steps based on the specific query context, enabling the system to adapt to diverse biological discovery needs without requiring users to manually reconfigure settings for each task

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The language machine learning model serves as a universal interface that handles multiple types of bio-activity discovery tasks through a single natural language processing mechanism. Instead of requiring separate configurations for different workflow types, the model understands various query formats and automatically routes them to appropriate tools and parameters, making the system versatile across different biological discovery scenarios

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If complex biological discovery pipeline workflows are executed in existing systems, then comprehensive analysis is possible, but the execution becomes inefficient and error-prone

Engineering Contradiction:
Improveworkflow execution accuracyVSAvoidworkflow complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The language machine learning model acts as an intermediary between user queries and the complex bio-activity discovery pipeline tools. It translates natural language intent into precise tool calls and parameter settings, mediating the complexity of workflow execution while maintaining reliability. The model ensures accurate tool selection and parameter passing, reducing errors that typically arise from manual configuration of complex workflows

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS20250225161A1Utilizing language machine learning models for autonomous executions of computerized tech-bio exploration tools
Publication Date: 2025.07.10 RECURSION PHARMACEUTICALS INC
  • US20250225161A1 patent drawing
  • US20250225161A1 patent drawing
  • US20250225161A1 patent drawing

AI summary

The present disclosure relates to systems, non-transitory computer-readable media, and methods for utilizing language machine learning model (LLM) as autonomous reasoners to navigate and execute multiple layers of a computerized bio-activity discovery pipeline of a tech-bio exploration system. In particular, the disclosed systems can utilize an LLM that learns to access one or more tech-bio exploration tools to execute one or more processes and/or tasks in a bio-activity discovery pipeline. For instance, the disclosed systems can provide an interactive query prompt interface to enable users to provide tech-bio queries (as prompts) and utilize the LLM with the prompts to execute one or more tasks in the bio-activity discovery pipeline to generate and/or retrieve bio-activity data for the query. Moreover, the disclosed systems can utilize one or more LLMs to autonomously utilize and/or interact with one or more tech-bio tools in the bio-activity discovery pipeline to generate and/or obtain bio-activity data.