Apparatus equipped with sample temperature control function

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Solution Overview

Problem

In air cooling systems for liquid chromatography autosamplers, external air inflow through the rack insertion opening can lead to dew condensation, causing operational malfunctions such as rusting and short-circuiting, especially when the sample rack is pulled out, due to the introduction of air with a higher dew point temperature.

Innovation Solution

The air temperature control system incorporates a rising guide to direct cooled air above the rack insertion opening when the sample rack is pulled out and an external air intake part to pressurize the temperature control space, reducing air inflow and preventing dew condensation by ensuring that external air is cooled and dehumidified before entering the space.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If the rack insertion opening is left open to allow easy access for sample rack insertion and removal, then ease of operation is improved, but external air inflow causes dew condensation leading to operational malfunctions

Engineering Contradiction:
Improveease of sample rack accessVSAvoidoperational reliability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

A seal member (flexible film/shell) is installed at the rack insertion opening to flexibly open when the sample rack is inserted or removed, and automatically close to seal the opening when the rack is not present, preventing external air inflow and dew condensation while maintaining ease of operation

Inventive Principle:
Principle #30Flexible shells and thin films

Solution Approach 2:

A guide member is introduced as an intermediary component to guide the sample rack during insertion and removal operations, ensuring proper alignment and smooth operation of the rack while the seal member remains closed, thus maintaining both ease of operation and reliability

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If a pull-out sample rack design is used for easy sample installation, then ease of operation is improved, but the rack insertion opening remains open during rack removal allowing external air to enter

Engineering Contradiction:
Improveease of sample installationVSAvoiddew condensation
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The seal member made of flexible material automatically conforms to the presence or absence of the pull-out sample rack, remaining closed to prevent dew condensation while allowing easy insertion and removal operations

Inventive Principle:
Principle #30Flexible shells and thin films

3Temperature

If the temperature control space is cooled to maintain sample temperature, then temperature control is improved, but the temperature difference with external air increases dew condensation risk when air enters

Engineering Contradiction:
Improvesample temperature controlVSAvoiddew condensation
Core Design Contradiction:
TemperatureVSObject-affected harmful factors

Solution Approach 1:

The seal member prevents the mixing of cooled air inside the temperature control space with warmer external air, eliminating dew condensation risk while maintaining effective temperature control for samples

Inventive Principle:
Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration effectively suppresses the inflow of external air and prevents dew condensation, maintaining the adiabatic sealing property of the temperature control space and preventing operational malfunctions.

Implementation Method 1

air in the temperature control space is cooled by a cooling element, such as a Peltier element

Methodology Applied
Scientific EffectHeat transfer: Conduction (thermal)

Implementation Method 2

a fan for blowing air taken in from the air intake portion toward the sample rack accommodated in the temperature control space

Methodology Applied
Scientific EffectForced convection: Forced Convection

Implementation Method 3

a rising guide to direct cooled air above the rack insertion opening when the sample rack is pulled out

Methodology Applied
Scientific EffectGravity-driven flow: Gravitation

Implementation Method 4

an external air intake part to pressurize the temperature control space, reducing air inflow and preventing dew condensation by ensuring that external air is cooled and dehumidified before entering the space

Methodology Applied
Scientific EffectPressure gradient: Pressure Gradient

Implementation Method 5

external air is cooled and dehumidified before entering the space

Methodology Applied
Scientific EffectCooling and dehumidification: Cooling

Data Source

PatentEP3591392B1Apparatus equipped with sample temperature control function
Publication Date: 2021.05.12 SHIMADZU CORP
  • EP3591392B1 patent drawingFigure 1
  • EP3591392B1 patent drawingFigure 2~3
  • EP3591392B1 patent drawingFigure 4

AI summary

To suppress inflow of external air through a rack insertion opening while a sample rack is pulled out. An apparatus includes a housing, a temperature control space, and an air temperature control part. The housing has the rack insertion opening on one side surface for putting in and taking out the sample rack. The air temperature control part has an air intake portion for intake of air in the temperature control space, a fan for blowing air taken in from the air intake portion toward the sample rack accommodated in the temperature control space, and a cooling element provided to cool the air on a path of air taken in from the air intake portion. The air temperature control part is configured to reduce an amount of air flowing near the rack insertion opening while the sample rack is pulled out from the temperature control space as compared to while the sample rack is accommodated in the temperature control space, so as to suppress inflow of air through the rack insertion opening.