Auxiliary Connection Device for Automated Cell Therapy Fluid Transfer
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Solution Overview
Problem
The manual transfer of cellular solutions between independent cell treatment devices in cell therapy processes is inefficient and prone to contamination, leading to suboptimal cell product quality.
Innovation Solution
An auxiliary connection device comprising a power unit and a liquid transfer tubing assembly with valves, which enables automated and controlled transfer of solutions between cell treatment devices, minimizing exposure to external environments and reducing contamination risks.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If manual transfer method is used to transfer cellular solution between cell treatment devices, then operation simplicity is maintained, but transfer efficiency is low and contamination risk increases
Solution Approach 1:
The patent introduces an auxiliary connection device as an intermediary component between cell treatment devices. This device includes a power unit that engages with liquid transfer tubing assemblies, serving as a mediator that enables automated liquid transfer without requiring direct integration between treatment devices. The power unit acts as a central control intermediary that coordinates fluid movement through multiple tubing assemblies connected to different treatment devices, thereby improving transfer efficiency while maintaining relative simplicity of individual devices.
2Reliability
If manual transfer of cellular solution is performed, then device structure remains simple, but contamination risk increases due to frequent operator handling
Solution Approach 1:
The auxiliary connection device serves as an intermediary that eliminates direct operator contact with cellular solutions during transfer operations. The power unit and tubing assembly system act as intermediaries between treatment devices, automating the transfer process and reducing contamination risks associated with manual handling while maintaining a relatively simple overall system architecture.
Solution Approach 2:
The patent replaces manual mechanical transfer operations with an automated power unit that drives liquid transfer through tubing assemblies. The power unit substitutes human operators in performing the transfer function, using mechanical actuation (such as peristaltic pumping) to move cellular solutions through the tubing system, thereby reducing contamination risk while adding controlled complexity to the system.
3Productivity
If automated liquid transfer is implemented using power unit and tubing assembly, then transfer efficiency improves and contamination risk reduces, but device complexity increases
Solution Approach 1:
The auxiliary connection device acts as an intermediary layer that manages the complexity of automated transfer operations. By centralizing the power unit and tubing assembly connections in a dedicated auxiliary device, the system maintains operational simplicity at the treatment device level while achieving automated high-efficiency transfer through the intermediary auxiliary system.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The auxiliary connection device enhances the efficiency of cell treatment processes by automating solution transfer, reducing manual handling, and minimizing contamination risks, thereby improving the quality and consistency of cell products.
Implementation Method 1
the power unit is a peristaltic pump, the peristaltic pump is located on the casing, and the first liquid transfer tubing engages with a pump head of the peristaltic pump
Implementation Method 2
the first valve, the second valve, the third valve and the fourth valve are pinch valves, and the pinch valves are connected to the side wall of the casing, wherein the pinch valves are located on an outer side of the liquid transfer tubing assembly
Data Source
AI summary
Provided in an embodiment of the present description is an auxiliary connection device which comprises a power unit and a liquid transfer tubing assembly. The liquid transfer tubing assembly comprises a first liquid transfer tubing. The first liquid transfer tubing comprises a first port and a second port. The power unit engages with the first liquid transfer tubing, and is located at a first liquid transfer tube between the first port and the second port.