Azole-azine Pesticide Compounds for Broad-Spectrum Insect Control
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Solution Overview
Problem
Current pesticides are inadequate in effectively controlling animal pests, particularly insects and acarines, due to limitations in their efficacy and specificity.
Innovation Solution
Development of novel pesticidally active azole azine compounds of formula I, which include specific structural components and agrochemically acceptable salts, stereoisomers, and N-oxides, for use in formulations that can be applied to control pests by forming acid addition salts or bases, enhancing their efficacy and application methods.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If current pesticides are used to control animal pests, then application can be performed with existing methods, but efficacy and specificity against insects and acarines are inadequate
Solution Approach 1:
The patent applies parameter changes by modifying the chemical structure of pesticide compounds through specific substituent patterns in the azole-azine core structure. Different substituents (R1-R6 groups including halogens, alkyl chains, cycloalkyl groups, and heteroaryl groups) are systematically varied to optimize binding affinity and biological activity against target pests, thereby improving efficacy while maintaining structural diversity for broad-spectrum activity
Solution Approach 2:
The patent employs composite materials by creating hybrid molecules that combine azole and azine functional groups within a single core structure. This composite approach integrates the beneficial properties of both heterocyclic systems, enabling the compound to interact with multiple pest targets and achieve both high efficacy and broad spectrum of activity simultaneously
2Reliability
If novel azole amide compounds are developed with specific structural components, then efficacy is improved, but structural complexity increases
Solution Approach 1:
The patent applies segmentation by dividing the complex molecule into distinct functional modules: a core azole-azine system (providing basic scaffolding and target binding), substituent groups R1-R3 (modifying electronic properties and metabolic stability), and side chains R4-R6 (controlling solubility, binding affinity, and selectivity). This modular design allows systematic optimization of efficacy while managing structural complexity through functional decomposition
Solution Approach 2:
The patent achieves universality by designing the azole-azine core structure to perform multiple functions simultaneously: it provides the fundamental binding interface for pest targets, accommodates diverse substituent patterns for optimizing activity, and enables formation of acid addition salts and stereoisomers that expand application versatility. This multi-functional core reduces the need for entirely separate molecular designs for different pest targets
Data Source
AI summary
Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides.