Three-Component Pesticidal Composition for Pathogen Control

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Solution Overview

Problem

Current pesticidal combinations for controlling pathogens and pests in plant propagation materials and plants are inadequate in terms of biological efficacy, phytotoxicity, and environmental and worker exposure, especially when pathogens become resistant to existing formulations.

Innovation Solution

A combination of at least three active ingredients: an azole fungicide (such as thiabendazole, ipconazole, or prothioconazole), a phenylamide fungicide (like mefenoxam, metalaxyl, or benalaxyl), and azoxystrobin, which demonstrate synergistic activity and are applied to plant propagation materials or their surroundings to control or prevent pathogenic and pest damage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If single active ingredients or simple combinations are used for pathogen control, then application rates can be kept low, but biological efficacy deteriorates when pathogens become resistant

Engineering Contradiction:
Improvepathogen control efficacyVSAvoidresistance to pathogen resistance
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines three different fungicides with distinct modes of action (azole, phenylamide, and strobilurin) into a single composition. This multi-component approach ensures that even if a pathogen is resistant to one ingredient, the other ingredients can still provide effective control, thereby overcoming pathogen resistance while maintaining reliable biological efficacy.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite pesticidal formulation integrating three chemically distinct fungicide classes. This composite structure provides synergistic effects and broad-spectrum activity against resistant pathogens, as each component contributes unique mechanisms of action that complement one another, preventing resistance development.

Inventive Principle:
Principle #40Composite materials

2Reliability

If higher application rates are used to overcome pathogen resistance, then biological efficacy improves, but environmental and worker exposure increases

Engineering Contradiction:
Improvepathogen control efficacyVSAvoidenvironmental and worker exposure
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

By combining three fungicides at optimized low rates, the formulation achieves high pathogen control efficacy without requiring high application rates. The synergistic interaction between components allows each ingredient to work at sub-optimal individual rates while collectively providing superior control, thereby reducing environmental and worker exposure.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent optimizes the concentration parameters of each fungicide component to achieve synergistic effects at low overall application rates. By carefully adjusting the ratios and amounts of azole, phenylamide, and strobilurin components, the formulation maximizes efficacy while minimizing the total active ingredient load applied to the environment.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If existing pesticidal combinations are used, then some pathogen control is achieved, but phytotoxicity increases

Engineering Contradiction:
Improvepathogen controlVSAvoidphytotoxicity
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent carefully optimizes the concentration parameters of each fungicide component to achieve effective pathogen control while maintaining safety for the plant. By adjusting the ratios of azole, phenylamide, and strobilurin and controlling individual component levels, the formulation prevents phytotoxic reactions that occur with higher concentrations of single ingredients or incompatible combinations.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP2077720B1Pesticidal compositions comprising an azole, a phenylamide and azoxystrobin
Publication Date: 2010.02.03 SYNGENTA PARTICIPATIONS AG

AI summary

A method of controlling or preventing pathogenic damage or pest damage in a plant propagation material, a plant, parts of a plant and/or plant organs that grow at a later point in time, which comprises applying on the plant, part of the plant, or surroundings thereof, a pesticidal combination comprising, for example, at least three active ingredient components optionally together with one or more customary formulation auxiliaries, wherein component (I) is one or more of an -azole fungicide selected from thiabendazole, oxpoconazole, ipconazole and prothioconazole, component (II) is one or more of a phenylamide fungicide, and component (III) is azoxystrobin, in any desired sequence or simultaneously.