Azoxystrobin Cyproconazole Chlorothalonil Fungicide Formulation
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
The inefficiency of existing fungicides in controlling Asian soybean rust, particularly due to resistance mechanisms developed by the fungus, and the need for a formulation that enhances the persistence and effectiveness of active ingredients like azoxystrobin and cyproconazole, while reducing degradation and environmental impact.
Innovation Solution
A concentrated fungicidal composition of azoxystrobin, cyproconazole, and chlorothalonil with a photoprotective effect, combined with a surfactant system, to increase the concentration and persistence of these active ingredients on plant leaves, reducing drift losses and photodegradation, and enhancing their fungicidal action.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing fungicides are used to control Asian soybean rust, then initial disease control is achieved, but the fungus develops resistance mechanisms that reduce long-term effectiveness
Solution Approach 1:
The patent combines three fungicides with different modes of action (azoxystrobin - QoI inhibitor, cyproconazole - DMI inhibitor, and chlorothalonil - multi-site blocker) into a single formulation. This merging of multiple chemical agents targeting different fungal metabolic pathways prevents resistance development while maintaining effective disease control over extended periods.
Solution Approach 2:
The formulation uses a composite approach by integrating multiple active ingredients with complementary mechanisms of action. The combination creates a synergistic effect where each component addresses different aspects of fungal pathology, ensuring both immediate efficacy and sustained protection against resistant strains.
2Reliability
If higher concentrations of fungicides are applied to overcome resistance, then disease control improves, but environmental impact and degradation increase
Solution Approach 1:
The patent optimizes the concentration parameters of each active ingredient within specific ranges (azoxystrobin: 1-10%, cyproconazole: 1-10%, chlorothalonil: 10-50%) to achieve maximum efficacy at minimal effective doses. This parameter optimization ensures sufficient disease control while minimizing environmental load and degradation products.
Solution Approach 2:
The formulation incorporates chlorothalonil as a short-persistence protective fungicide that provides immediate barrier protection but degrades relatively quickly, reducing long-term environmental accumulation. This is balanced with longer-persistence systemic ingredients for sustained internal protection.
3Duration of action of stationary object
If fungicides are applied frequently to maintain control, then disease protection is sustained, but application costs and resource consumption increase
Solution Approach 1:
The formulation ensures continuous protective action by combining preventive (chlorothalonil) and curative (azoxystrobin and cyproconazole) mechanisms. The different persistence profiles and modes of action of the three ingredients work in sequence and overlap to provide uninterrupted disease protection, extending the interval between applications.
Solution Approach 2:
The formulation includes chlorothalonil as a protective agent that acts preliminarily to prevent spore germination and initial infection. This preliminary barrier action reduces the need for subsequent curative treatments, extending protection duration and reducing application frequency.
4Ease of operation
If conventional formulations are used, then application is straightforward, but active ingredient persistence on leaf surfaces is reduced due to drift losses and photodegradation
Solution Approach 1:
The patent incorporates adjuvants and surfactants as intermediary substances that mediate between the active ingredients and the leaf surface. These intermediaries enhance adhesion, reduce drift, and provide photoprotection, thereby extending the persistence of active ingredients on foliage without complicating the application process.
Solution Approach 2:
The formulation converts the harmful effect of sunlight (which causes photodegradation) into a beneficial effect by using chlorothalonil and other ingredients that absorb UV radiation, protecting the more sensitive azoxystrobin and cyproconazole from degradation while maintaining their bioactivity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The formulation significantly improves the control of Asian rust and other diseases by maintaining high levels of azoxystrobin and cyproconazole on plant surfaces, reducing environmental impact, and minimizing application doses and frequency, thereby increasing crop productivity and extending fungicidal effects.
Implementation Method 1
chlorothalonil with photoprotective effect, reducing the degradation of azoxystrobin and cyproconazole and other strobilurins and triazoles
Implementation Method 2
a surfactant system properly balanced, with surfactants that have dispersing and wetting characteristics
Implementation Method 3
increased deposition with reduced drift losses
Data Source
AI summary
The present invention describes a concentrated fungicidal composition of azoxystrobin, cyproconazole and chlorothalonil of high load and of other formulations containing chlorothalonil with photoprotective effect of azoxystrobin, cyproconazole and other active ingredients and/or derivatives of this composition, as well as the method of treatment of diseases caused by fungi.