B1+ Mapping via Magnetization Reset and Spiral Readouts

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Solution Overview

Problem

High-field MRI at 3 T experiences significant B1+ field inhomogeneity, particularly in abdominal and cardiac imaging, leading to nonuniform image signal and contrast, which existing double-angle methods cannot effectively address due to long TR requirements and motion compensation issues.

Innovation Solution

The proposed method combines a double-angle approach with a B1-insensitive magnetization reset sequence and interleaved spiral readouts, allowing for rapid B1+ mapping by lifting the dependence on T1 and enabling multi-slice acquisition within a single breathhold.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If double-angle method is used for B1+ mapping, then measurement accuracy is improved, but scan time increases due to long TR requirements

Engineering Contradiction:
ImproveB1+ mapping accuracyVSAvoidscan time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

A non-selective saturation pulse is applied before each double-angle acquisition to pre-reset the longitudinal magnetization. This preliminary action ensures that magnetization recovery is not dependent on the long TR required by conventional double-angle methods, thereby reducing scan time while maintaining measurement accuracy

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The method changes the TR parameter from conventional long values (several seconds) to short values (4-8 ms) by introducing magnetization reset pulses. This parameter change enables rapid B1+ mapping while preserving the accuracy of the double-angle measurement technique

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If conventional double-angle method is used, then B1+ field can be measured, but motion artifacts increase in areas prone to motion

Engineering Contradiction:
ImproveB1+ field measurementVSAvoidimage quality in motion-prone areas
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The method rushes through the data acquisition process by using very short TR values (4-8 ms) enabled by magnetization reset pulses. This rapid acquisition skips through the time window where motion artifacts would normally degrade image quality in motion-prone areas like chest and abdomen

Inventive Principle:
Principle #21Skipping (Rushing through)

3Area of stationary object

If multi-slice acquisition is performed, then imaging coverage is improved, but scan time increases

Engineering Contradiction:
Improveimaging coverageVSAvoidscan time
Core Design Contradiction:
Area of stationary objectVSLoss of time

Solution Approach 1:

The magnetization reset pulses enable continuous rapid acquisitions across multiple slices without requiring long TR intervals between slices. This continuity of useful action allows multi-slice B1+ mapping to be completed within a single breathhold, improving coverage while minimizing scan time

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method provides accurate B1+ maps with reduced scan time and improved image quality, maintaining agreement with reference methods while reducing scan time from several seconds to a few seconds, even in areas prone to motion, such as the chest and abdomen.

Implementation Method 1

a B1-insensitive magnetization reset sequence at the end of each data acquisition, which lifts the dependence of TR on T1

Methodology Applied
Scientific EffectMagnetization reset: Magnetic Field

Implementation Method 2

exciting nuclear spins in the object with a RF magnetic field (B1), and then detecting signals emitted by the excited spins as they precess within the magnetic field (B0)

Methodology Applied
Scientific EffectRF excitation: Electromagnetic Induction

Implementation Method 3

interleaved spiral readouts, enabling multi-slice acquisition of B1+ maps in a short time

Methodology Applied
Scientific EffectSpiral readout: Magnetic Field

Data Source

PatentUS7446526B2RF field mapping for magnetic resonance imaging
Publication Date: 2008.11.04 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
  • US7446526B2 patent drawing
  • US7446526B2 patent drawing
  • US7446526B2 patent drawing

AI summary

For in vivo magnetic resonance imaging at high field (≧3 T) it is essential to consider the homogeneity of the active B1 field (B1+), particularly if surface coils are used for RF transmission. A new method is presented for highly rapid B1+ magnitude mapping. It combines the double angle method with a B1-insensitive magnetization-reset sequence such that the choice of repetition time (TR) is independent of T1 and with a multi-slice segmented (spiral) acquisition to achieve volumetric coverage with adequate spatial resolution in a few seconds.