Multi-Strain Bacillus and Enzyme Feed Additives for Poultry

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Solution Overview

Problem

Animal feeds face challenges in achieving optimal nutrient utilization and growth due to variations in raw material composition, and existing methods to improve animal health through direct-fed microbials and enzymes are not fully effective in enhancing performance metrics like weight gain and feed efficiency.

Innovation Solution

A composition comprising multi-strain direct-fed microbials such as B. subtilis and B. licheniformis, combined with exogenous enzymes like xylanase, amylase, and protease, is administered to animals to enhance nutrient availability and absorption, thereby improving growth parameters and reducing incidence of lesions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If single-strain direct-fed microbials or single enzymes are used, then the composition is simpler and easier to manufacture, but the animal performance improvement is insufficient

Engineering Contradiction:
Improveanimal performanceVSAvoidcomposition complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent combines multiple Bacillus strains (B. subtilis, B. licheniformis) with multiple enzyme types (xylanase, amylase, protease) into a single integrated feed composition. This merging approach creates a synergistic effect where the microbials and enzymes work together to improve nutrient digestion, absorption, and animal performance beyond what single components could achieve alone.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite feed additive comprising different biological agents (Bacillus strains) and enzymatic components in specific combinations. This composite structure leverages the complementary functions of each component - the microbials provide probiotic benefits and enzyme production, while the exogenous enzymes provide immediate digestive assistance, resulting in enhanced overall efficacy.

Inventive Principle:
Principle #40Composite materials

2Productivity

If multi-strain direct-fed microbials and multiple enzymes are combined, then animal performance significantly improves, but the composition becomes more complex and difficult to manufacture

Engineering Contradiction:
Improveweight gain and feed efficiencyVSAvoidcomposition formulation
Core Design Contradiction:
ProductivityVSEase of manufacture

Solution Approach 1:

The patent divides the complex composition into distinct functional modules: specific Bacillus strains (B. subtilis 27, B. subtilis BS2084, B. subtilis 3AP4, B. licheniformis 842, B. licheniformis 21) and specific enzyme types (xylanase, amylase, protease). Each component is selected and formulated at optimized levels to perform specific functions, making the manufacturing process more systematic and controllable despite the multi-component nature.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention optimizes specific parameters including the strain selection criteria, enzyme activity units, ratios between different components, and inclusion levels in feed. By establishing precise parameter ranges and specifications for each component, the patent enables standardized manufacturing processes that ensure consistent product quality and performance outcomes.

Inventive Principle:
Principle #35Parameter changes

3Stability of the object's composition

If natural raw materials are used in feed, then the feed composition is simpler, but the nutrient composition varies greatly leading to inconsistent animal performance

Engineering Contradiction:
Improvenutrient composition consistencyVSAvoidfeed formulation complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent incorporates mechanisms to monitor and adjust nutrient delivery based on the variable composition of natural raw materials. The multi-strain Bacillus formulation and enzyme combination act as a feedback system that compensates for variations in raw material quality, ensuring consistent nutrient availability and animal performance regardless of feedstock variability.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The Bacillus strains and enzymes serve as intermediary agents that bridge the gap between variable natural raw materials and consistent nutrient delivery. These biological additives break down complex and variable plant materials into consistent, bioavailable nutrients, stabilizing the effective nutrient composition reaching the animal regardless of raw material fluctuations.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combination of multi-strain direct-fed microbials and exogenous enzymes significantly increases average daily weight gain, feed conversion efficiency, and reduces the incidence of paw lesions in poultry, leading to improved overall animal performance and economic benefits.

Implementation Method 1

A composition comprising multi-strain direct-fed microbials such as B. subtilis and B. licheniformis, combined with exogenous enzymes like xylanase, amylase, and protease

Methodology Applied
Scientific EffectEnzyme: Enzyme

Implementation Method 2

direct-fed microbials such as B. subtilis and B. licheniformis

Methodology Applied
Scientific EffectFermentation: Fermentation

Implementation Method 3

exogenous enzymes like xylanase, amylase, and protease

Methodology Applied
Scientific EffectEnzyme: Enzyme

Data Source

PatentUS10463701B2Blends of <i>Bacillus </i>strains and enzymes
Publication Date: 2019.11.05 INT N&H DENMARK APS

AI summary

Compositions and methods are disclosed for providing beneficial effects to animals, including but not limited to increasing performance of the animal. In one embodiment, the animal is poultry. In another embodiment, the disclosure relates to a composition comprising one or more direct-fed microbials and one or more exogenous feed enzymes.