Bacillus and Lactic Acid Bacterial Mixture for Ungulate Foot Infections
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Solution Overview
Problem
Current treatments for lameness in ungulates, such as antibiotics and disinfectants, are inadequate in preventing and addressing podal infections, often leading to environmental concerns and resistance issues, and existing alternatives like probiotics lack efficacy and general applicability.
Innovation Solution
A composition combining specific strains of Bacillus and lactic bacteria, including Bacillus subtilis and Lactococcus lactis/Pediococcus pentosaceus, is used to treat and prevent bacterial or parasitic podal infections in ungulates, applied in a form suitable for spraying or foot baths to improve animal health and reduce lameness.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If antibiotics and disinfectants are used to treat podal infections, then infection control is improved, but environmental pollution and bacterial resistance increase
Solution Approach 1:
The patent changes the fundamental parameter of the treatment agent from conventional antibiotics/disinfectants to specific probiotic bacterial strains (Bacillus subtilis, Lactococcus lactis, Pediococcus pentosaceus). This parameter change transforms the treatment mechanism from direct pathogen elimination to competitive exclusion and immune modulation, thereby maintaining infection control while eliminating environmental pollution and resistance issues associated with conventional agents
Solution Approach 2:
The patent employs benign, self-depleting probiotic bacteria that naturally colonize the foot environment and then die off, leaving no persistent harmful residues. These short-living probiotic strains replace long-lasting but environmentally harmful antibiotics and disinfectants, providing effective treatment without lingering environmental pollution or resistance development
2Reliability
If formol and copper sulfate are used for foot baths, then disease control effectiveness is improved, but toxicity to humans and environment increases
Solution Approach 1:
The patent converts the harmful toxic substances (formol, copper sulfate) into beneficial probiotic bacteria. The probiotics perform the disease control function through competitive exclusion and immune stimulation, while being inherently non-toxic to humans and the environment. This transformation maintains disease control effectiveness while eliminating the toxicity problem
Solution Approach 2:
The patent introduces probiotic bacteria as intermediary agents between the animal foot and the pathogenic environment. These intermediary probiotics mediate the protective effect without requiring direct contact with harmful chemicals, thereby maintaining disease control while eliminating toxicity to humans and the environment
3Reliability
If probiotics are applied to treat dermatitis, then immune defense is stimulated, but efficacy and general applicability are insufficient
Solution Approach 1:
The patent creates a universal probiotic formulation containing multiple bacterial strains (Bacillus subtilis, Lactococcus lactis, Pediococcus pentosaceus) that can effectively treat various podal infections across different animal species. This multi-functional approach enhances both efficacy and general applicability compared to single-strain probiotics, while maintaining immune defense stimulation
Solution Approach 2:
The patent employs a composite probiotic mixture combining different bacterial genera and species that work synergistically. This composite formulation provides broader spectrum coverage and enhanced efficacy compared to single probiotic strains, while maintaining the immune stimulation benefit. The composite nature allows application across various infection types and animal species
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The bacterial mixture effectively improves the quality of life for ungulates by limiting bacterial progression and preventing lameness, offering a preventative effect by controlling pathogenic bacteria proliferation, as demonstrated in trials with dairy cattle and ovine herds.
Implementation Method 1
The bacterial mixture effectively improves the quality of life for ungulates by limiting bacterial progression and preventing lameness, offering a preventative effect by controlling pathogenic bacteria proliferation
Implementation Method 2
The invention is based on the surprising finding by the inventors that the combination of bacteria of the genus Bacillus and lactic bacteria significantly improves the condition of ungulates suffering from lameness caused by a parasitic or bacterial podal infection
Data Source
AI summary
The invention relates to the use of a bacterial mixture for the prevention and improvement of the state of ungulates suffering from pathologies involving a parasitic or bacterial infection of the foot, said composition comprising: at least one strain of bacteria of the genus Bacillus, and at least one lactic acid bacterium.