Bacterial Supply System for Personalized Microbiome Treatment

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Solution Overview

Problem

Current methods lack a systematic approach to select and supply specific bacteria necessary for improving health conditions, particularly in treating conditions like cardiovascular diseases, as they struggle with bacterial colonization and individualized bacterial flora supplementation.

Innovation Solution

A database and bacterial flora bank system is constructed to associate health condition changes of donors with their bacterial flora, allowing for the selection and supply of necessary bacteria to test subjects based on their health condition changes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If feces from healthy donors are transplanted to treat intestinal dysbiosis, then the patient's symptoms can be improved, but the bacterial flora may not colonize effectively because the donor's bacteria are not adapted to the recipient's individual needs

Engineering Contradiction:
Improvesymptom improvementVSAvoidbacterial colonization
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent applies preliminary action by constructing a database and bacterial flora bank in advance, where bacterial flora from multiple donors is collected, stored, and characterized before needed. This allows the system to pre-analyze and match bacteria to recipient needs, rather than randomly selecting donor feces at the time of treatment. The database stores information about bacterial composition and health outcomes, enabling informed selection of appropriate bacteria for each patient's specific condition.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent applies local quality by selecting specific bacteria from the donor pool based on the recipient's individual needs and health condition. Rather than transplanting all bacteria from a donor's feces, the system identifies and selects only the bacterial strains that are most beneficial for that particular patient's condition, creating a personalized treatment approach that addresses specific local deficiencies in the patient's microbiome.

Inventive Principle:
Principle #3Local quality

2Adaptability or versatility

If bacterial flora from multiple donors are stored and selected based on health condition changes, then personalized treatment can be achieved, but the system complexity increases due to database construction and bacterial selection processes

Engineering Contradiction:
Improvepersonalized treatmentVSAvoidsystem complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent applies copying by creating a digital representation (database) of the bacterial flora characteristics and health outcomes from multiple donors. Instead of physically handling and testing numerous bacterial samples, the system stores digital records of bacterial composition, donor health information, and treatment outcomes. This digital copy allows rapid querying and selection of appropriate bacteria without the complexity of physical sample management, reducing operational complexity while maintaining personalized treatment capability.

Inventive Principle:
Principle #26Copying

3Reliability

If specific bacteria are selected and supplied to improve health conditions, then treatment efficacy increases, but the time and resources required for bacterial selection and preparation increase

Engineering Contradiction:
Improvetreatment efficacyVSAvoidbacterial selection time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-collecting, characterizing, and storing bacterial flora from multiple donors in a organized database and bank system before treatment is needed. Bacterial strains are pre-screened and associated with specific health conditions and outcomes. When a patient requires treatment, the system can quickly query the database and retrieve pre-prepared bacterial strains matched to the patient's condition, avoiding the time-consuming process of selecting and preparing bacteria from scratch at the time of treatment.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20220367021A1Bacterial supplying system
Publication Date: 2022.11.17 NOSTER INC
  • US20220367021A1 patent drawing

AI summary

A system that stores bacterial flora of donors, selects a bacterium necessary for improving bacterial flora according to the health condition of a test subject, and supplies the same in a utilizable state to the test subject is provided.