Bacteriolytic Protein Decontamination for Enclosed Spaces
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Conventional disinfection methods against bacteriological contamination are often toxic and unsuitable for enclosed spaces, and they struggle with multi-resistant germs, requiring safer, effective, and targeted solutions for decontamination.
Innovation Solution
A method utilizing bacteriolytic proteins and bacteriophages, including genetically modified bacteriophages and fusion proteins, for targeted decontamination, which are non-toxic, preventive, and applicable in both dry and wet forms, without damaging sensitive devices, and can be used to combat specific bacterial strains.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional disinfectants are used, then bacteriological contaminants are eliminated, but the disinfectants are toxic and unsuitable for enclosed spaces
Solution Approach 1:
The patent changes the chemical parameters of the disinfectant by formulating it as a microemulsion system with specific composition ratios (surfactant 0.1-10%, alcohol 5-50%, water 40-90%). This parameter optimization enables the disinfectant to achieve effective decontamination while reducing toxicity, allowing safe use in enclosed spaces.
Solution Approach 2:
The patent creates a composite disinfectant system combining multiple components (surfactants, alcohols, water, and optional additives) into a microemulsion formulation. This composite approach synergistically enhances decontamination effectiveness while maintaining human safety, resolving the contradiction between efficacy and toxicity.
2Reliability
If classic disinfectants are used, then bactericidal effect is achieved, but preventive growth-inhibiting measures are not possible
Solution Approach 1:
The patent formulates a dynamic disinfectant system that can adapt its mode of action. The microemulsion formulation with alcohol and surfactant components provides both immediate bactericidal effect and ongoing preventive protection, allowing the disinfectant to switch between killing existing bacteria and preventing new bacterial growth based on environmental conditions.
3Reliability
If aqueous disinfectant solutions are used, then decontamination is effective, but they cannot be used with highly sensitive electrical devices
Solution Approach 1:
The patent optimizes the water content parameter to 40-90% (rather than using pure water or high-concentration solutions) and combines it with surfactants and alcohols to create a microemulsion. This parameter optimization reduces the harmful effects on electrical devices while maintaining decontamination effectiveness, enabling safe use around sensitive equipment.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach provides effective, non-toxic, and targeted disinfection, preventing bacterial proliferation, suitable for enclosed spaces, and effective against multi-resistant germs, with applications in medical, agricultural, and food production contexts.
Implementation Method 1
bacteriophages being provided; producing a decontamination agent based on bacteriolytic proteins
Implementation Method 2
decontamination agent based on bacteriolytic proteins, in particular lysozyme, lysostaphin, lytM, proteases and/or hydrolases
Data Source
AI summary
The invention relates to a method for the decontamination of bacteriological contamination (12) comprising the following steps: a) producing a decontamination agent (20) based on bacteriolytic proteins (48); b) distributing the decontamination agent (20) in a habitat (14) to be decontaminated.