Liquid-Supply Bag With Horizontal Discharge Pipe for Reduced Dead Volume
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Solution Overview
Problem
Existing bags used for housing samples and reagents in the preparation of induced pluripotent stem cells (iPS cells) face issues with efficient liquid discharge and storage, leading to dead volumes and inaccuracies in supply due to their soft material composition.
Innovation Solution
A bag design featuring a housing part with a discharging part and discharging pipe device, including a discharging path, energizing part, and cylindrical member, which facilitates horizontal extension of the discharging pipe to prevent hanging and dead volumes, ensuring accurate liquid supply to a closed-system flow channel.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If the discharging pipe extends vertically downward, then the bag structure is simple, but the discharging pipe hangs down causing dead volume and inaccurate liquid supply
Solution Approach 1:
The discharging pipe is configured to extend in the horizontal direction rather than vertically downward, changing the spatial dimension of pipe extension. This horizontal configuration prevents the pipe from hanging down and eliminating dead volume, while maintaining bag structure simplicity through the natural flexibility of the soft material bag
2Ease of operation
If the bag is made of soft material, then the bag is flexible and easy to handle, but the discharging pipe hangs down creating dead volume
Solution Approach 1:
By extending the discharging pipe horizontally rather than vertically, the patent utilizes the horizontal dimension to prevent pipe sagging. The soft material bag's flexibility is maintained while the horizontal pipe configuration leverages the bag's ability to maintain shape in the horizontal plane, preventing dead volume formation
3Volume of stationary object
If multiple bags are arranged closely for efficient space utilization, then space efficiency improves, but bags may wrinkle and narrow affecting liquid discharge
Solution Approach 1:
The patent applies different structural characteristics to different parts of the bag. The discharging pipe region is configured with horizontal extension and specific structural features that prevent wrinkling and narrowing, while other parts of the bag maintain soft material flexibility. This localized structural differentiation ensures reliable liquid discharge even when bags are arranged closely
Data Source
AI summary
A bag according to an embodiment includes a housing part, a discharging part, and a discharging pipe device. The housing part includes a housing chamber that houses a liquid as a sample or a reagent. The discharging part includes a discharging path configured to discharge the liquid from the housing chamber. The discharging pipe device is connected to the discharging part, and discharges the liquid from the housing chamber via the discharging path. The discharging pipe device is connected to the discharging part to extend from the discharging part toward a direction having a horizontal direction component.


