Balloon Catheter Continuous Fluid Circulation for Thermal Ablation

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Standard balloon catheters face challenges in maintaining constant pressure and volume during infusion, especially in thermal ablation applications where the surrounding tissue acts as a thermal sink, rapidly dissipating heat from the balloon.

Innovation Solution

A system with a catheter having an inflow and outflow lumen, a balloon in fluid communication with these lumens, and an infusion device that continuously circulates fluid into and out of the balloon to maintain constant pressure and volume, while optionally heating the fluid to maintain a consistent temperature for thermal ablation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Temperature

If a standard balloon catheter is used for thermal ablation, then the balloon can be positioned at the target tissue, but the surrounding tissue acts as a thermal sink that rapidly dissipates heat from the balloon, preventing effective thermal transfer

Engineering Contradiction:
Improveballoon temperatureVSAvoidheat dissipation
Core Design Contradiction:
TemperatureVSLoss of energy

Solution Approach 1:

The system continuously circulates heated fluid through the balloon catheter, maintaining constant temperature and pressure. The infusion device continuously replenishes the heated fluid in the balloon, ensuring uninterrupted thermal energy delivery to the target tissue despite the thermal sink effect of surrounding tissues.

Inventive Principle:
Principle #20Continuity of useful action

2Temperature

If fluid is continuously circulated through the balloon to maintain temperature, then thermal transfer to target tissue is improved, but the balloon volume and pressure may fluctuate, compromising continuous tissue contact

Engineering Contradiction:
Improvefluid temperatureVSAvoidballoon volume and pressure
Core Design Contradiction:
TemperatureVSStability of the object's composition

Solution Approach 1:

The system employs feedback control where pressure sensors monitor balloon pressure and the infusion device adjusts fluid circulation accordingly. The system continuously monitors balloon pressure and temperature, and automatically adjusts the infusion rate to maintain constant balloon volume and pressure while ensuring continuous heated fluid circulation for effective thermal ablation.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution allows for continuous tissue contact and effective thermal transfer to the target tissue by maintaining the balloon at a constant volume and pressure, overcoming the limitations of standard balloon catheters.

Implementation Method 1

The infusion device may further comprise a heating mechanism to heat the fluid to generate a heated fluid

Methodology Applied
Scientific EffectHeating: Heating

Implementation Method 2

a surface of the balloon overlying one or more of the heated compartments allows heat from the heated fluid to transfer to and ablate a target tissue

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Implementation Method 3

a surface of the balloon overlying one or more of the heated compartments allows heat from the heated fluid to transfer to and ablate a target tissue adjacent to the surface

Methodology Applied
Scientific EffectThermal ablation: Ablation

Data Source

PatentEP3267955B1Continuous flow balloon catheter systems and methods of use
Publication Date: 2025.06.04 PAVMED INC
  • EP3267955B1 patent drawingFigure 1
  • EP3267955B1 patent drawingFigure 2A
  • EP3267955B1 patent drawingFigure 2B

AI summary

Systems and methods for continuous infusion of a fluid, which may be heated, into a balloon catheter. A system for balloon inflation, the system comprising a catheter having an inflow lumen and an outflow lumen, a balloon positioned at a distal end of the catheter, the balloon being in fluid communication with the inflow and the outflow lumen, and an infusion device in fluid communication with the balloon through the inflow and outflow lumens, the infusion device configured for continuously circulating a fluid into and out of the balloon to maintain the balloon at a constant pressure and volume by matching a flow of the fluid into the balloon via the inflow lumen with a flow of the fluid out of the balloon via the outflow lumen in order to keep the balloon volume and pressure constant during an entire infusion.