Balloon Catheter Light Distribution for Bladder Tumor Treatment
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Solution Overview
Problem
Current light treatment systems for bladder tumors face challenges in effectively treating the lower part of the bladder due to limited light irradiation time, as prolonged irradiation leads to urine accumulation, reducing treatment effectiveness, and existing systems struggle to efficiently illuminate the entire bladder surface, especially the lower regions where tumors often remain undetected or untreated.
Innovation Solution
A light treatment system comprising a probe with an optical fiber and a light emitter inserted into a balloon catheter with a reflector and a distal end portion that divides the bladder into regions, allowing for focused light reflection and scattering to ensure even illumination of the bladder, including the lower parts, using a liquid with light scattering particles and a flexible, mirror-coated reflector to enhance light distribution.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Area of stationary object
If light irradiation time is extended to treat the entire bladder surface, then treatment coverage is improved, but urine accumulates in the bladder reducing light intensity and treatment effectiveness
Solution Approach 1:
The balloon catheter is divided into multiple light-emitting sections (first, second, third light emitters at different positions) that can be activated sequentially or simultaneously. This segmentation allows the treatment to be divided into multiple stages, enabling complete bladder surface coverage while maintaining adequate light intensity by treating different regions in sequence rather than attempting to illuminate the entire surface at once.
Solution Approach 2:
The patent employs periodic activation of different light emitters in sequence. The first light emitter treats the anterior wall, then the second and third light emitters treat other regions in subsequent time periods. This periodic action allows urine to be partially drained or redistributed between treatment phases, preventing excessive urine accumulation that would attenuate light intensity while still achieving comprehensive coverage over the treatment cycle.
2Reliability
If high power treatment light is used to maintain effectiveness during longer irradiation, then treatment effectiveness is improved, but the risk of tissue damage and complications increases
Solution Approach 1:
The total treatment energy is segmented across multiple low-power light emitters positioned at different locations within the balloon catheter. Instead of using one high-power emitter that risks tissue damage, the patent distributes the treatment burden across several emitters (first, second, third light emitters), each delivering lower power that is safer for surrounding tissues while collectively achieving the required total energy dose for effective treatment.
Solution Approach 2:
The patent applies partial action by using multiple light emitters that each deliver a portion of the total required treatment energy. The first light emitter provides treatment to the anterior wall, while second and third emitters provide treatment to other regions. This partial action approach ensures that no single emitter delivers excessive energy that could cause tissue damage, while the cumulative effect of all emitters achieves the necessary total energy dose for reliable treatment effectiveness.
3Ease of operation
If a rigid endoscope is used for TUR-Bt, then the upper part of the bladder can be observed and treated, but the lower part behind the endoscope is difficult to detect and treat
Solution Approach 1:
The patent transitions from the one-dimensional linear approach of a rigid endoscope to a three-dimensional omnidirectional approach using a balloon catheter with multiple light emitters positioned at different spatial locations (anterior, lateral, posterior walls). This dimensional change allows light to be delivered from multiple directions simultaneously, enabling detection and treatment of tumors in the lower bladder region that would be obscured from the single viewing angle of a rigid endoscope.
Solution Approach 2:
The balloon catheter with multiple light emitters serves multiple functions: it can treat tumors on the anterior wall (first light emitter), lateral walls (second light emitter), and posterior wall (third light emitter). This multi-functional design replaces the need for multiple separate procedures or instruments, providing universal coverage of all bladder regions including the lower part that is difficult to access with a rigid endoscope alone.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system achieves effective treatment of the entire bladder, including hard-to-reach lower regions, by reflecting and scattering light to ensure thorough illumination, even with low-power treatment light, thereby improving treatment outcomes and reducing the risk of residual tumors.
Implementation Method 1
an optical fiber configured to propagate light
Implementation Method 2
a reflector configured to reflect the light emitted by the light emitter
Implementation Method 3
The balloon is filled with a scattering medium including fat emulsion diluted with a physiological saline solution. Therefore, the treatment light is scattered
Data Source
AI summary
A light treatment system includes: a probe configured to be inserted into a bladder, the probe including an optical fiber configured to propagate light, and a light emitter that is provided at a distal end of the optical fiber, the light emitter being configured to emit the light; and a balloon catheter into which the probe is inserted, the balloon catheter being configured to be inserted into the bladder, the balloon catheter including a distal end portion that is to be dilated in the bladder, a wall configured to divide inside of the distal end portion into two regions, and a reflector configured to reflect the light emitted by the light emitter, the reflector being provided on a surface of the wall, the surface facing a region of the two regions, the region being where the light emitter is positioned.


