Balloon Catheter Stable Expansion Drug Delivery
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Solution Overview
Problem
Existing balloon catheters are ineffective in delivering drugs to hardened stenosis or lesion parts due to calcification, as they require higher expansion pressures to expand and deliver drugs deeply, but existing technologies struggle to maintain a stable expansion pressure range without excessive radial expansion.
Innovation Solution
A balloon catheter design with a drug-coated outer surface, featuring a reinforcement pattern and materials that maintain a consistent outer diameter and length change ratio at high pressures, allowing for effective expansion and drug delivery to calcified areas without excessive radial expansion.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If the balloon is pressurized at high expansion pressure (24-28 atm) to expand hardened stenosis parts, then the drug can be delivered deeply into the stenosis part, but the balloon may excessively expand in the radial direction causing harm to normal blood vessel walls
Solution Approach 1:
The balloon is designed with different structural characteristics in different regions: the straight tube part has controlled expansion properties to prevent excessive radial expansion, while other parts may have different compliance characteristics. This local differentiation allows the balloon to deliver drugs deeply into hardened stenosis parts without excessively expanding normal blood vessel walls.
Solution Approach 2:
The patent specifies precise parameter ranges for the balloon structure, including the outer diameter change ratio of the straight tube part being 1.1% or less when pressurized from 24 atm to 28 atm. By controlling these parameters, the balloon maintains stable expansion characteristics that enable deep drug delivery while preventing damage to normal blood vessel walls.
2Stability of the object's composition
If the balloon is designed to maintain stable outer diameter at high pressures, then drug delivery to hardened stenosis is effective, but the balloon may not expand enough to deliver drug deeply
Solution Approach 1:
The balloon incorporates a straight tube part with specific structural properties that provide stable outer diameter control, while other portions of the balloon can expand adequately to deliver drugs deeply into stenosis parts. This local differentiation resolves the contradiction between stability and expansion capability.
Solution Approach 2:
The balloon is constructed with composite materials or multi-layer structures that provide both stability and expandability. The straight tube part uses materials or结构设计 that maintain dimensional stability at high pressures, while other parts have materials that allow sufficient expansion for deep drug delivery.
3Manufacturing precision
If the balloon expands significantly in radial direction to reach hardened stenosis, then drug can be delivered to the stenosis part, but the expansion pressure becomes unstable and difficult to control
Solution Approach 1:
The patent defines specific parameter ranges for the balloon structure, including the outer diameter change ratio of the straight tube part being 1.1% or less when pressurized from 24 atm to 28 atm. These parameter controls ensure that the balloon expands sufficiently to reach hardened stenosis while maintaining stable expansion pressure.
Data Source
AI summary
A balloon catheter includes a shaft, and a balloon provided outside the shaft. A drug is provided on an outer surface of the balloon, and the balloon has at least a straight tube part. A change ratio of an outer diameter of the straight tube part, (D28−D24)/D24, is 1.1% or less. D24 is the outer diameter of the straight tube part when an internal pressure of 2.43 MPa (24 atm) is applied, and D28 is the outer diameter of the straight tube part when an internal pressure of 2.84 MPa (28 atm) is applied.