Degradable Joint Balloon Composition Neutralizing Acidic Byproducts
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Solution Overview
Problem
Degradable polymer materials used in joint balloons produce acidic byproducts during degradation, leading to tissue inflammation and limiting their application.
Innovation Solution
A composition for degrading joint balloons is developed, comprising 90-99.9% degradable polymer material, 0.1-10% nano hydroxide (such as nano magnesium hydroxide), and 0.1-2% dispersant, which helps in reducing acidic inflammation by neutralizing acidic byproducts.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If degradable polymer material is used for joint balloon, then the joint balloon can be completely degraded and absorbed after injury recovery, but acidic byproducts are produced during degradation which induce tissue inflammation
Solution Approach 1:
The patent converts the harmful acidic byproducts into beneficial neutral substances by incorporating basic substances (calcium carbonate, magnesium hydroxide, or aluminum hydroxide) into the polymer composition. These basic substances neutralize the acidic degradation products in situ, transforming the harmful acidification effect into a beneficial pH-balancing effect that prevents tissue inflammation while maintaining complete degradability.
Solution Approach 2:
The patent introduces basic substances as intermediary components that mediate between the degradable polymer material and the surrounding tissue. These intermediaries (calcium carbonate, magnesium hydroxide, or aluminum hydroxide) accept protons from acidic byproducts, preventing direct contact between acidic substances and tissue, thus eliminating inflammation while allowing complete degradation.
2Duration of action of stationary object
If degradable polymer material is used for joint balloon, then the joint balloon degrades completely after use, but the acidic environment reduces application reliability
Solution Approach 1:
The patent transforms the harmful acidic degradation environment into a beneficial neutral environment by incorporating basic substances that neutralize acids. This allows the joint balloon to maintain its temporary support function throughout the degradation period without causing inflammation, thereby preserving application reliability while achieving complete degradation.
Solution Approach 2:
The patent creates a composite material system combining degradable polymer with basic substances (calcium carbonate, magnesium hydroxide, or aluminum hydroxide). This composite structure maintains the temporary mechanical support properties of the polymer while the basic substances counteract acidic byproducts, ensuring reliable performance throughout the degradation period without tissue inflammation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively reduces acid inflammation by neutralizing acidic byproducts and optimizes the bursting pressure and flexibility of the degradable joint balloon, enhancing its performance and safety.
Implementation Method 1
the acidic byproducts easily induce tissue inflammation... nano hydroxide... neutralizing acidic byproducts
Data Source
AI summary
The present application relates to a composition for degrading a joint balloon and use thereof as well as the degradable joint balloon and a preparation method thereof. The composition for degrading the joint balloon comprises the following components in parts by weight: 90-99.9 parts of degradable polymer material, 0.1-10 parts of nano hydroxide and 0.1-2 parts of dispersant; the nano hydroxide is selected from nano magnesium hydroxide and nano calcium hydroxide. Provided is use of the composition for degrading the joint balloon in preparation of the degradable joint balloon. The degradable joint the balloon is prepared by using composition. The preparation method of the degradable joint balloon is selected from a dip coating method, an electrostatic spinning method, an extrusion method, an injection molding method, a blow molding method and a mould pressing method.