Multi-Directional Barbed Sutures for Secure Nerve Tissue Fixation

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Solution Overview

Problem

Existing sutures, particularly for nerve tissue repair, require precise microsurgical techniques and can damage nerve structures, and do not effectively prevent movement in multiple directions, making them challenging and time-consuming to use.

Innovation Solution

Development of barbed sutures with multi-directional barbs formed by angled cuts on the suture surface, allowing for rapid attachment and resistance to movement in multiple directions, and optionally combined with a base membrane or mesh for enhanced tissue repair.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional sutures are used for nerve tissue repair, then secure attachment can be achieved, but the procedure requires skilled microsurgical techniques and may damage critical nerve structures

Engineering Contradiction:
Improvesecure attachmentVSAvoidsurgical technique complexity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The barbed suture is designed to self-grasp tissue through its barbs, eliminating the need for complex knot-tying techniques. The barbs automatically engage with the tissue upon insertion and maintain fixation without requiring skilled microsurgical manipulation for securing the suture.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The suture is divided into multiple barbed segments along its length, with each barb acting as an independent anchoring point. This segmentation allows the suture to engage tissue at multiple locations simultaneously, providing secure fixation while simplifying the insertion process.

Inventive Principle:
Principle #1Segmentation

2Reliability

If traditional sutures are used for nerve tissue repair, then attachment can be achieved, but the procedure is time-intensive

Engineering Contradiction:
Improveattachment securityVSAvoidprocedure time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The barbed design allows the suture to self-anchor into tissue without requiring time-consuming knot-tying procedures. The barbs automatically engage with the tissue upon insertion and maintain fixation, significantly reducing the time required for suture placement while maintaining secure attachment.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The barbs are pre-formed on the suture before implantation, eliminating the need to create fixation elements during the surgical procedure. This preliminary preparation of the fixation structure allows for rapid deployment during surgery.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If traditional sutures are used, then attachment can be achieved, but they do not effectively prevent movement in multiple directions

Engineering Contradiction:
Improveattachment securityVSAvoidmulti-directional resistance
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The barbs are designed with asymmetric geometry, featuring a sharp leading edge for easy penetration and a broader base for secure engagement. This asymmetric shape allows the barbs to effectively resist pull-out forces while maintaining adaptability to tissue movement in various directions.

Inventive Principle:
Principle #4Asymmetry

Solution Approach 2:

The barbed suture adds a dimensional element to traditional linear sutures by incorporating protruding barbs that extend radially from the suture body. This three-dimensional structure provides resistance to movement in multiple directions, not just along the suture axis.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

4Object-affected harmful factors

If precise suture placement in the epineurium is attempted, then nerve structure protection can be achieved, but the procedure becomes technically challenging

Engineering Contradiction:
Improvenerve structure damageVSAvoidplacement precision requirement
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The barbed suture design allows for self-guided placement into the epineurium through the mechanical engagement of barbs with the tissue layer. The barbs naturally engage with the epineurial tissue upon insertion, providing inherent guidance and feedback that simplifies precise placement without requiring complex positioning techniques.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS20260108245A1Barbed devices for securing tissue
Publication Date: 2026.04.23 AXOGEN CORP
  • US20260108245A1 patent drawing
  • US20260108245A1 patent drawing
  • US20260108245A1 patent drawing

AI summary

A barbed suture may include a body and a plurality of barbs. The body may include a substantially flat surface extending along a longitudinal axis of the body, and the plurality of barbs may be formed on a surface of the body that is not the substantially flat surface. The body may have a non-circular cross-sectional shape, and the plurality of barbs may be formed along a longitudinal axis of the body on a corner of the cross-sectional shape. A tissue repair device may include a base membrane and a plurality of barbed sutures attached to the base membrane.