Basic pH Self-Adhesive Resin Cement for Tooth Remineralization

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Solution Overview

Problem

Conventional dental cements have acidic compositions, leading to issues like tooth sensitivity, inhibition of remineralization, and promotion of cavity growth, making it difficult to develop self-adhesive resin cements with a basic pH.

Innovation Solution

A two-component self-adhesive resin cement system with a 1:1 weight ratio of acidic monomers and basic fillers such as Portland cement, tricalcium silicate, or calcium oxide, which is initially acidic but polymerizes to a basic pH, facilitating bonding and promoting remineralization.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If acidic monomers are used in self-adhesive resin cements to enable self-etching and adhesion, then bonding strength is improved, but tooth sensitivity and inhibition of remineralization occur

Engineering Contradiction:
Improvebonding strengthVSAvoidtooth sensitivity and inhibition of remineralization
Core Design Contradiction:
StrengthVSObject-affected harmful factors

Solution Approach 1:

The invention changes the pH parameter of the cement composition by incorporating basic fillers (calcium hydroxide, calcium oxide, or basic calcium carbonate) to neutralize or counterbalance the acidic monomers. This parameter change allows the cement to maintain self-etching capability while reducing harmful acidic effects on tooth structure and promoting remineralization.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention creates a composite material system combining acidic monomers (for adhesion) with basic fillers (for pH neutralization). This composite approach allows both functions to coexist: the acidic monomers provide self-etching and bonding, while the basic fillers mitigate harmful effects and promote remineralization.

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If basic pH is achieved in dental cements to promote remineralization and inhibit bacterial growth, then remineralization and antibacterial effects are improved, but self-adhesive bonding capability deteriorates

Engineering Contradiction:
Improveremineralization promotion and bacterial inhibitionVSAvoidself-adhesive bonding capability
Core Design Contradiction:
Object-affected harmful factorsVSStrength

Solution Approach 1:

The basic fillers are incorporated into the cement composition in advance to neutralize the acidic monomers after polymerization. This preliminary preparation ensures that the harmful acidic effects are counterbalanced while the bonding function is already established through the acidic monomers' self-etching action.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The invention converts the harmful acidic by-products of polymerization into a beneficial basic pH environment. The basic fillers transform the potentially harmful acidic atmosphere into a beneficial alkaline environment that promotes remineralization and inhibits bacterial growth, while the acidic monomers continue to provide adhesion.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Strength

If conventional acidic composition is used to achieve self-etching, then adhesion to tooth structure is improved, but promotion of cavity growth and pulpal inflammation occurs

Engineering Contradiction:
Improveadhesion to tooth structureVSAvoidcavity growth and pulpal inflammation
Core Design Contradiction:
StrengthVSObject-generated harmful factors

Solution Approach 1:

The acidic monomers perform their useful self-etching function, and then the basic fillers convert the harmful acidic by-products into beneficial basic pH conditions. This transforms the harmful acidic environment into a beneficial alkaline environment that inhibits bacterial growth and promotes healing.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The pH parameter is changed from acidic to basic through the incorporation of basic fillers. This parameter change occurs after the acidic monomers have performed their adhesion function, allowing the cement to transition from an acidic state (good for bonding) to a basic state (good for health promotion).

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The basic pH self-adhesive resin cement achieves improved bonding strength and remineralization, inhibiting bacterial growth and secondary caries, while maintaining polymerization efficiency and strength.

Implementation Method 1

The composition has a pH before polymerization of about pH 4 or less and a pH after polymerization of about pH 8 or more

Methodology Applied
Scientific EffectHydration reaction: Hydrates

Data Source

PatentEP3515986B1Dental self-adhesive resin cement
Publication Date: 2022.03.09 BISCO INC

AI summary

A dental self-adhesive resin cement is provided comprising a two-component system. A first catalyst component includes one or more acidic monomers. A second base component includes one or more basic fillers. The mixture of the first and second components is polymerizable and has an initial pH that is acidic immediately after mixing and a pH of at least about pH 8 after polymerization.