BASS Bean Plant Genetic Modification for Trait Stability
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Solution Overview
Problem
Current bean plant breeding methods face challenges in developing stable, high-yielding bean plants with desirable traits such as disease resistance, drought tolerance, and improved nutritional quality, which are not adequately addressed by existing technologies.
Innovation Solution
The development of a novel bean plant designated BASS, along with methods for vegetative propagation, tissue culture, and genetic modification using techniques like CRISPR/Cas system, Zinc finger nucleases, and backcrossing to introduce desired traits like herbicide resistance, disease resistance, and enhanced nutritional quality.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If conventional bean plant breeding methods are used, then traditional variety development is possible, but the ability to introduce specific desirable traits such as disease resistance, drought tolerance, and improved nutritional quality is limited
Solution Approach 1:
The patent replaces conventional mechanical breeding methods (crossing, selection, and hybridization) with genetic engineering techniques including CRISPR/Cas system, Zinc finger nucleases, and direct gene insertion. This substitution enables precise introduction of specific traits such as disease resistance, drought tolerance, and nutritional quality without relying on traditional complex breeding programs
Solution Approach 2:
The patent applies parameter changes by modifying specific genetic parameters directly through genetic engineering. Instead of changing traits through multiple generations of breeding, the invention directly alters genetic parameters by inserting, deleting, or modifying specific genes to achieve desired phenotypic changes in disease resistance, stress tolerance, and nutritional composition
2Stability of the object's composition
If traditional breeding methods are used to develop high-yielding varieties, then yield improvement is possible, but stability and consistency of desired traits across generations are not adequately achieved
Solution Approach 1:
The patent applies preliminary action by pre-introducing desired traits through genetic engineering before field testing and commercial deployment. The CRISPR/Cas system and other genetic modification techniques allow the desired traits to be established in the genome beforehand, ensuring stability across generations without requiring extensive multi-generation breeding programs to fix traits
Solution Approach 2:
The patent uses copying by inserting replicated copies of desired genes into the bean plant genome. Through genetic engineering, specific genes conferring desirable traits are copied and inserted into target plants, ensuring consistent expression of these traits across generations without the variability inherent in traditional breeding methods
3Adaptability or versatility
If existing breeding technologies are used, then variety development is possible, but adequate addressing of disease resistance, drought tolerance, and nutritional quality simultaneously is not achieved
Solution Approach 1:
The patent applies segmentation by addressing each desired trait (disease resistance, drought tolerance, nutritional quality) as a separate genetic target that can be independently modified. The CRISPR/Cas system and other genetic engineering techniques allow sequential or simultaneous modification of specific genes for each trait, enabling reliable introduction of multiple traits without the unpredictable interactions that occur in traditional polygenic breeding programs
Data Source
AI summary
Novel bean plants, such as bean designated BASS are disclosed. In some embodiments, the disclosure relates to the seeds of bean plant BASS, to the plants and plant parts of bean BASS, and to methods for producing a bean plant by crossing the bean plant BASS with itself or another bean plant. The disclosure further relates to methods for producing other bean plants derived from the bean BASS.