Batch Swine Management for Fixed-Time AI Farrowing Rate

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Solution Overview

Problem

Batch management systems in swine farming face challenges with reduced farrowing rate and litter size due to embryo overcrowding and absorption during pregnancy, which are not effectively addressed by existing methods like nutrition supplementation and assisted heat detection.

Innovation Solution

Administering 1-[bis(4-cyanophenyl)alkyl]-1,2,4-triazole to synchronize follicular development and regulate the expression of genes in the LPA signaling pathway, combined with exogenous gonadotropins and ovulation induction drugs, to improve embryo spacing and farrowing efficiency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If batch management systems with fixed-time artificial insemination are used to synchronize estrus and mating, then production efficiency and bio-safety are improved, but farrowing rate and number of piglets born alive decrease due to embryo overcrowding and absorption

Engineering Contradiction:
Improveproduction efficiencyVSAvoidfarrowing rate
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies parameter changes by introducing a chemical substance that modifies physiological parameters during pregnancy. This substance regulates embryo spacing by affecting the LPA signaling pathway, changing the physical or chemical state of the uterine environment to prevent embryo overcrowding while maintaining the benefits of batch management systems.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If batch management systems with fixed-time artificial insemination are used to synchronize estrus and mating, then production efficiency and bio-safety are improved, but number of piglets born alive decreases due to embryo absorption during pregnancy

Engineering Contradiction:
Improveproduction efficiencyVSAvoidnumber of piglets born alive
Core Design Contradiction:
ProductivityVSQuantity of substance

Solution Approach 1:

The patent uses parameter changes by administering a chemical substance that alters the physiological parameters of the uterus during pregnancy. This regulates the LPA signaling pathway to control embryo spacing and prevent absorption, thereby increasing the number of piglets born alive while maintaining synchronized batch management.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If nutrition supplementation and assisted heat detection are used to address farrowing rate issues, then some improvement is achieved, but the problems of embryo overcrowding and absorption are not effectively addressed

Engineering Contradiction:
Improvefarrowing rateVSAvoideffectiveness of existing methods
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent introduces a chemical substance as an intermediary to address the core problem of embryo overcrowding. This substance acts as a mediator that regulates the LPA signaling pathway, providing a more effective solution than traditional nutrition supplementation or heat detection methods by directly influencing embryo spacing and prevention of absorption.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS20250332222A1Batch management method for improving farrowing rate or number of piglets born alive in swine
Publication Date: 2025.10.30 CHINA AGRI UNIV
  • US20250332222A1 patent drawing
  • US20250332222A1 patent drawing
  • US20250332222A1 patent drawing

AI summary

The disclosure relates to a batch management method for improving the farrowing rate or the number born alive in swine. It includes the following steps: synchronization of estrus in swine are used an exogenous gonadotropin(s) to synchronize follicular development, and then fed with 1-[bis(4-cyanophenyl)alkyl]-1,2,4-triazole after 6-12 hours. Next the gilts or sows are bred in batches after treated with ovulation-inducing drug(s). The disclosure can effectively alleviate decreased farrowing rate and number of piglets born alive in the batch gilts or sows used the fixed-time artificial insemination, without influencing the serum estrogen level, estrus and ovulation time in mated gilts or sows. Therefore, a novel method for improving the reproductive efficiency of gilts or sows will be established, which is valuable for popularizing batch farrowing in swine including with fixed-time artificial insemination.