Bayesian Target-Region Prediction With Uncertainty-Guided Label Screening

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Solution Overview

Problem

Existing methods for predicting target parts in medical images using artificial neural networks face accuracy and reliability issues due to noise in medical images and insufficient training data, leading to uncertainties in predicted results.

Innovation Solution

A method and apparatus that utilize a Bayesian neural network-based predictive model to calculate clinical parameters by estimating predictive distributions and incorporating uncertainty data, such as aleatoric and epistemic uncertainties, to improve the accuracy and reliability of predicted results.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If an artificial neural network is used to predict target parts from medical images, then the time required for identification is reduced, but the accuracy and reliability of predicted results are lowered due to noise in medical images and insufficient training data

Engineering Contradiction:
Improvetime required for identificationVSAvoidaccuracy and reliability of predicted results
Core Design Contradiction:
Loss of timeVSReliability

Solution Approach 1:

The patent implements a feedback mechanism where uncertainty information from the predictive model is fed back into the system to guide active learning. The system calculates uncertainty data (aleatoric and epistemic uncertainty) from predicted results and uses this feedback to screen and select medical images for labeling, which are then used to retrain and improve the predictive model, creating a continuous improvement loop that enhances reliability over time.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system performs self-service by automatically screening medical images based on calculated uncertainty data and selecting images that would be most beneficial for model training. Instead of requiring manual selection of training images, the system autonomously identifies which images have high epistemic uncertainty and would provide the most value for improving the model, thereby serving itself in the active learning process.

Inventive Principle:
Principle #25Self-service

2Reliability

If visual checking by specialists is used to identify target parts, then diagnostic accuracy can be maintained, but the time and resources required increase significantly with the number of patients

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidprocessing capacity per expert
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent introduces an intermediary system that acts as a bridge between automated AI prediction and expert verification. The predictive model with uncertainty calculation serves as an intermediary that pre-screens and prioritizes images, allowing specialists to focus their expertise on cases with high uncertainty or potential abnormalities rather than reviewing every image, thus maintaining diagnostic accuracy while improving productivity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

Instead of requiring full expert review of all medical images, the system applies partial action by using the automated predictive model to handle the majority of routine cases with high confidence. Experts only need to perform excessive action (detailed review) on the small subset of images that the system identifies as having high uncertainty or potential issues, thereby maintaining diagnostic accuracy while significantly reducing the overall time and resource investment required.

Inventive Principle:
Principle #16Partial or excessive action

3Loss of time

If a predictive model trained with a small number of training data is used, then the initial deployment time is reduced, but the accuracy and reliability of predicted results are further lowered

Engineering Contradiction:
Improvemodel training timeVSAvoidaccuracy of predicted results
Core Design Contradiction:
Loss of timeVSMeasurement precision

Solution Approach 1:

The system performs preliminary action by initially deploying a predictive model trained with a small number of training data to quickly start the active learning process. This preliminary model, though not highly accurate initially, is sufficient to generate predictions and calculate uncertainty data, which then guide the selection of images for labeling and subsequent retraining, enabling the model to progressively improve accuracy over time.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent ensures continuity of useful action by implementing a continuous active learning loop where the predictive model continuously generates predictions, uncertainty is continuously calculated, images are continuously screened and selected for labeling, and the model is continuously retrained with new labeled data. This continuous cycle maintains and progressively improves measurement precision over time, transforming the initial limitation of small training data into a strength through ongoing learning.

Inventive Principle:
Principle #20Continuity of useful action

Data Source

PatentUS20250308018A1Method and apparatus for providing clinical parameter for predicted target region in medical image, and method and apparatus for screening medical image for labeling
Publication Date: 2025.10.02 ONTACT HEALTH CO LTD
  • US20250308018A1 patent drawing
  • US20250308018A1 patent drawing
  • US20250308018A1 patent drawing

AI summary

Provided according to an embodiment of the present invention are a method and an apparatus for providing uncertainty data for a predicted target region in a medical image. Also provided according to an embodiment of the present invention are a method and an apparatus for screening a medical image for labeling.