Belt-Based Bead Separation Using Reduced Pressure

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Solution Overview

Problem

Current methods for generating and collecting beads using microfluidic technology are inefficient, particularly due to batch-wise filtration and manual oven-drying processes, which hinder large-scale production and automation.

Innovation Solution

A semi-continuous apparatus and method involving a microfluidic device or piezoelectric droplet generator for bead generation, with a bead-receiving means that moves beads from a fluid removal zone to a collection zone using reduced pressure, facilitating efficient separation and collection of beads from a carrier fluid.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If batch-wise filtration is used to separate beads from carrier fluid, then separation can be achieved, but the process efficiency is low and automation is difficult

Engineering Contradiction:
Improvebead production efficiencyVSAvoidautomation capability
Core Design Contradiction:
ProductivityVSExtent of automation

Solution Approach 1:

The patent implements a continuous process where the belt moves continuously through different zones (deposition zone, drying zone, collection zone) allowing uninterrupted bead production and separation, eliminating the batch-wise operation of traditional filtration methods

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent replaces manual filtration and oven-drying operations with an automated belt system that uses controlled airflow and mechanical movement to achieve separation and drying, enabling easy automation

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If filtration and oven-drying are used for bead processing, then beads can be separated and dried, but the process cannot be automated easily and does not lend itself to producing large amounts of beads

Engineering Contradiction:
Improvelarge-scale production capabilityVSAvoidprocess automation difficulty
Core Design Contradiction:
ProductivityVSEase of manufacture

Solution Approach 1:

The patent uses a dynamic belt system that can move at controlled speeds through different processing zones, allowing flexible adjustment of processing parameters and easy integration with automated control systems for large-scale production

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent divides the processing into distinct zones along the belt (deposition zone, drying zone, collection zone), with each zone performing a specific function, allowing independent optimization and easy automation of each segment

Inventive Principle:
Principle #1Segmentation

3Productivity

If a stationary bead-receiving means is used, then the device structure is simple, but the productivity is limited due to batch processing

Engineering Contradiction:
Improvebead collection efficiencyVSAvoiddevice structure
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent employs a moving belt instead of a stationary receiving means, allowing continuous transport of beads through processing zones and enabling continuous production without significantly increasing device complexity

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The moving belt serves multiple functions: receiving beads, transporting them through drying zones, and delivering them to collection points, replacing multiple separate components with a single multi-functional element

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables efficient, automated, and scalable production of beads by moving beads from a fluid removal zone to a collection zone using reduced pressure, improving efficiency and scalability over traditional batch processes.

Implementation Method 1

a fluid removal means operable to remove fluid from the bead-receiving means in a first fluid removal zone by the application of reduced pressure

Methodology Applied
Scientific EffectReduced pressure: Vacuum

Implementation Method 2

a bead collection means operable to remove beads from the bead-receiving means in a bead collection zone by the application of reduced pressure

Methodology Applied
Scientific EffectReduced pressure: Vacuum

Data Source

PatentEP2736621B1Device and method for producing and collecting beads
Publication Date: 2022.01.26 MIDATECH PHARMA (WALES) LTD
  • EP2736621B1 patent drawingFigure 1
  • EP2736621B1 patent drawingFigure 2
  • EP2736621B1 patent drawingFigure 3~4

AI summary

A device is provided for separating beads from a carrier fluid, the device comprising: a bead-receiving means for receiving beads dispersed in a carrier fluid, a fluid removal means operable to remove fluid from the bead-receiving means in a first fluid removal zone by the application of reduced pressure, and a bead collection means operable to remove beads from the bead-receiving means in a bead collection zone by the application of reduced pressure, the bead-receiving means being movable so that beads are movable from the first fluid removal zone to the bead collection zone.