3D Beam-Forming X-Ray Target for Conformal Dose Control

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Conventional miniature X-ray sources used in intraoperative radiotherapy (IORT) are expensive, have a limited operating life, may not provide optimal voltage for therapeutic effects, and have difficulty in controlling radiation characteristics for conformal radiation therapy.

Innovation Solution

A method and system for controlling an electron beam to generate X-ray radiation by positioning a target element in the beam's path, using a beam-former structure to control the beam pattern and direction, and varying the electron beam's intersection location with the target element to adjust the X-ray dose and radiation direction.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If conventional miniature X-ray sources are used for IORT, then the X-ray source can be positioned close to the tumor bed, but the operating life is very limited and the source must be replaced after a limited number of patients

Engineering Contradiction:
Improveoperating life of X-ray sourceVSAvoidreliability of X-ray source
Core Design Contradiction:
Duration of action of moving objectVSReliability

Solution Approach 1:

The target is divided into multiple independently controllable target segments, each capable of being selectively bombarded by the electron beam. This segmentation allows the system to extend operating life by distributing wear across multiple segments and enables reliable operation by maintaining consistent performance through selective use of healthy segments.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system dynamically changes operational parameters including electron beam voltage, current, and target segment selection to optimize performance and extend operating life. By varying these parameters, the system can operate at lower intensities when possible and switch between target segments to distribute wear, thereby improving both duration of action and reliability.

Inventive Principle:
Principle #35Parameter changes

2Duration of action of moving object

If conventional miniature X-ray sources are used for IORT, then the X-ray source can be compact, but the expense is very high due to limited useful operating life requiring frequent replacement

Engineering Contradiction:
Improveoperating life of X-ray sourceVSAvoidcost of X-ray source
Core Design Contradiction:
Duration of action of moving objectVSQuantity of substance

Solution Approach 1:

The target is divided into multiple independently controllable target segments, each capable of being selectively bombarded by the electron beam. This segmentation allows the system to extend operating life by distributing wear across multiple segments and enables reliable operation by maintaining consistent performance through selective use of healthy segments.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system maintains continuous useful action by automatically switching between multiple target segments as they are bombarded by the electron beam. This continuous operation without interruption extends the effective operating life of the X-ray source, reducing the frequency of replacement and associated costs.

Inventive Principle:
Principle #20Continuity of useful action

3Power

If conventional miniature X-ray sources are used for IORT, then the X-ray source can be small, but the voltage available is moderately high and may not be optimal for the desired therapeutic effect

Engineering Contradiction:
Improvevoltage of X-ray sourceVSAvoidtherapeutic effectiveness
Core Design Contradiction:
PowerVSReliability

Solution Approach 1:

The system dynamically changes operational parameters including electron beam voltage, current, and target segment selection to optimize performance and extend operating life. By varying these parameters, the system can operate at lower intensities when possible and switch between target segments to distribute wear, thereby improving both duration of action and reliability.

Inventive Principle:
Principle #35Parameter changes

4Ease of operation

If conventional miniature X-ray sources are used for IORT, then the X-ray source can be compact, but the radiation characteristics are difficult to control for conformal radiation therapy

Engineering Contradiction:
Improvecontrol of radiation characteristicsVSAvoidprecision of radiation delivery
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The target is divided into multiple independently controllable target segments, each capable of being selectively bombarded by the electron beam. This segmentation allows the system to extend operating life by distributing wear across multiple segments and enables reliable operation by maintaining consistent performance through selective use of healthy segments.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system dynamically controls which target segments are bombarded by the electron beam based on real-time treatment requirements. This dynamic control enables precise adjustment of radiation characteristics including beam direction, intensity distribution, and spatial pattern, achieving conformal radiation therapy with high precision.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for precise control of X-ray beam direction and pattern, extending the operating life of X-ray sources, reducing costs, and improving the suitability for conformal radiation therapy by optimizing X-ray delivery.

Implementation Method 1

A very high voltage of 50 kV up to 250 kV is applied across the cathode and the anode, and a relatively low voltage is applied to a filament to heat the cathode. The filament produces electrons (by means of thermionic emission, field emission, or similar means)

Methodology Applied
Scientific EffectThermionic emission: Thermionic Emission

Implementation Method 2

The high voltage potential between the cathode and the anode causes electrons to flow across the vacuum from the cathode to the anode with a very high velocity

Methodology Applied
Scientific EffectElectron acceleration by electric field: Electric Field

Implementation Method 3

When the electrons are decelerated in the target material of the anode, they produce X-rays

Methodology Applied
Scientific EffectBremsstrahlung radiation:

Implementation Method 4

The wavelengths of X-ray radiation most commonly used for IORT purposes correspond to a type of X-ray radiation that is sometimes referred to as fluorescent X-rays, characteristic X-rays, or Bremsstrahlung X-rays

Methodology Applied
Scientific EffectCharacteristic X-ray emission:

Data Source

PatentUS12027341B2Three-dimensional beam forming X-ray source
Publication Date: 2024.07.02 EMPYREAN MEDICAL SYSTEMS INC
  • US12027341B2 patent drawing
  • US12027341B2 patent drawing
  • US12027341B2 patent drawing

AI summary

X-ray target element is comprised of a planar wafer. The planar wafer element includes a target layer and a substrate layer. The target layer is comprised of an element having a relatively high atomic number and the substrate layer is comprised of diamond. The substrate layer is configured to support the target layer and facilitate transfer of thermal energy away from the target layer.