Beet Plant Extract Composition for Psoriasis Treatment
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Solution Overview
Problem
Current treatments for psoriasis, including topical and systemic therapies, often result in incomplete remission of symptoms and significant secondary effects due to systemic absorption, highlighting the need for more effective and side-effect-free alternatives.
Innovation Solution
A composition based on biologically active components extracted from the beet plant (Beta vulgaris subspecies cicla) is used topically or orally to treat psoriasis and inflammatory skin conditions, utilizing a physiologically acceptable solvent and carrier to deliver the extract effectively.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If topical preparations containing cortisone preparations or vitamin D analogues are applied on large areas of affected skin, then anti-inflammatory treatment effect is improved, but systemic absorption occurs causing significant secondary effects
Solution Approach 1:
The patent extracts and utilizes natural active compounds (beta-sitosterol, flavonoids, phenolic compounds) from beet plant (Beta vulgaris subspecies cicla) to replace synthetic cortisone preparations and vitamin D analogues. This extraction of beneficial natural components provides anti-inflammatory treatment effect while avoiding the harmful systemic absorption associated with conventional medications.
Solution Approach 2:
The patent employs a natural, renewable plant-based resource (beet plant) as a disposable, biodegradable alternative to persistent synthetic pharmaceuticals. The vegetal extract can be applied topically without accumulating in the system, providing effective treatment without long-term secondary effects from systemic absorption.
2Reliability
If conventional topical treatments are used, then some symptom remission is achieved, but complete remission is only obtained in a small percentage of cases
Solution Approach 1:
The patent utilizes a composite mixture of multiple active compounds naturally present in the beet plant, including beta-sitosterol, flavonoids (quercetin, kaempferol, myricetin), and phenolic compounds. This composite of synergistic natural substances provides superior complete remission rates compared to single-component conventional treatments.
Solution Approach 2:
The patent changes the chemical composition parameters of the treatment by replacing synthetic pharmaceutical compounds with natural plant-derived compounds. This parameter change in substance composition fundamentally improves the remission achievement rate while maintaining safety.
3Stability of the object's composition
If emollient substances such as petrolatum are applied, then skin barrier function is temporarily improved, but the underlying inflammatory condition and hyperproliferation are not effectively treated
Solution Approach 1:
The beet plant extract serves multiple functions simultaneously: it provides anti-inflammatory action to treat the underlying condition, modulates keratinocyte proliferation to address hyperproliferation, and maintains skin barrier function. This multi-functionality replaces the need for separate emollient and anti-inflammatory treatments.
Solution Approach 2:
The patent extracts the essential therapeutic components from the beet plant that possess both barrier-protecting and anti-inflammatory properties, eliminating the need to use separate petrolatum-based emollients that only provide temporary barrier function without treating the underlying inflammation.
Data Source
AI summary
The present invention concerns, in one aspect, a composition comprising an extract of beet plant in a biologically active amount and a physiologically acceptable excipient or carrier. The composition of the invention finds application in the dermatological or cosmetic treatment of inflammatory skin affection such as reddening or psoriatic lesions.