Beta Component Magazine for Sterile Pharmaceutical Barrier Transfer
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Solution Overview
Problem
Existing transfer systems for barrier systems in pharmaceutical production facilities have limited receiving capacity, requiring frequent docking and undocking of beta components, which increases the risk of contamination and reduces efficiency.
Innovation Solution
A transfer system with a beta component featuring a magazine device that holds multiple objects, allowing for simultaneous sterilization and efficient transfer of objects between the operating and isolation regions, utilizing a magazine device with receptacles and a centering device for precise positioning.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If a single beta component is used with limited receiving capacity, then the device complexity is reduced, but the productivity decreases due to frequent docking and undocking operations
Solution Approach 1:
The beta component is segmented into a magazine device with multiple receptacles, allowing multiple objects to be held simultaneously. This segmentation enables batch transfer operations, improving productivity without requiring multiple separate beta components.
Solution Approach 2:
The magazine device serves multiple functions: it holds multiple objects, enables simultaneous sterilization of all objects, and allows sequential access to each receptacle. This multi-functionality improves transfer efficiency without proportionally increasing device complexity.
2Reliability
If beta components are frequently docked and undocked, then the receiving capacity limitation is addressed, but the reliability decreases due to increased contamination risk
Solution Approach 1:
Multiple objects are pre-loaded into the magazine device's receptacles before docking with the alpha component. This preliminary action allows all objects to be transferred in one docking operation, eliminating repeated docking/undocking cycles and maintaining sterility while improving productivity.
Solution Approach 2:
The magazine device enables continuous transfer operations by maintaining a stock of pre-loaded objects. Once docked, multiple objects can be sequentially transferred without undocking, ensuring continuous sterile operation and eliminating interruptions that compromise reliability.
3Productivity
If multiple beta components are used to increase receiving capacity, then the productivity improves, but the device complexity and operation difficulty increase
Solution Approach 1:
Multiple receptacles are merged into a single magazine device structure that functions as one beta component. This consolidation provides high transfer capacity while simplifying operation, as the entire magazine is docked and undocked as a single unit rather than managing multiple separate beta components.
Solution Approach 2:
The magazine device utilizes vertical stacking or radial arrangement of receptacles to increase capacity without increasing the horizontal footprint. This dimensional optimization allows high receiving capacity while maintaining ease of docking and undocking operations.
Data Source
AI summary
The invention relates to a transfer system (1) for use in a barrier system (2) and to a beta component (8) for use in a transfer system (1) and to a barrier system (2) and to a production facility (3).