Beta-cyclocitric acid for plant drought tolerance

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Solution Overview

Problem

Current methods for enhancing drought tolerance in plants, such as chemical treatments and genetic engineering, face limitations, including potential negative effects on plant growth and variability in effectiveness across different species, necessitating an alternative approach to address drought-related stresses like wilting, leaf chlorosis, and reduced yields.

Innovation Solution

The use of β-cyclocitric acid or its salts, applied through foliar spraying, irrigation, or other methods, to improve drought tolerance in plants by preventing or delaying drought effects like wilting and reducing water needs, without significantly affecting stomatal closure or gas exchange, thus promoting recovery and shelf-life.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If abscisic acid or its analogs are applied to improve drought tolerance, then plant tolerance to drought stress is improved, but gas exchange is reduced and photosynthesis is slowed down

Engineering Contradiction:
Improvedrought toleranceVSAvoidphotosynthesis and plant growth
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent applies a different chemical compound (osmoprotectant) with different molecular properties and mechanism of action compared to abscisic acid. This chemical parameter change allows improving drought tolerance through osmotic adjustment without triggering stomatal closure, thereby maintaining photosynthesis and plant growth while enhancing drought resistance

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent introduces an intermediary substance (osmoprotectant) that mediates drought tolerance through a different physiological pathway than abscisic acid. Instead of acting as a signaling molecule that closes stomata, the osmoprotectant acts as a chemical intermediary that directly protects cellular structures and maintains osmotic balance, bypassing the harmful stomatal closure pathway

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If transgenic expression of drought tolerance genes is used, then crop performance under drought is improved, but genetic engineering complexity and regulatory constraints increase

Engineering Contradiction:
Improvedrought toleranceVSAvoidgenetic engineering process
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent replaces the complex genetic engineering system with a simpler chemical application system. Instead of modifying plant DNA and expressing transgenic proteins, the invention applies exogenous osmoprotectant chemicals that directly provide drought tolerance, substituting a complex biological engineering approach with a straightforward chemical treatment approach

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If osmo-protectants are applied to improve drought tolerance, then adaptive roles in osmotic adjustment are achieved, but not all plants are able to accumulate these compounds endogenously

Engineering Contradiction:
Improvedrought toleranceVSAvoidapplicability across plant species
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent enables plants to benefit from osmoprotectant application by providing exogenous compounds that the plant can directly utilize for osmotic adjustment. The applied osmoprotectants serve the plant's protective needs without requiring the plant to have endogenous synthesis capabilities, allowing universal applicability across species that cannot produce these compounds themselves

Inventive Principle:
Principle #25Self-service

Data Source

PatentEP3592148B1Use of beta-cyclocitric acid or a salt thereof to enhance plant tolerance to drought stress
Publication Date: 2024.07.31 COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
  • EP3592148B1 patent drawingFigure 1A~1C
  • EP3592148B1 patent drawingFigure 2A~2B
  • EP3592148B1 patent drawingFigure 2C

AI summary

The use of β-cyclocitric acid or a salt thereof for improving drought tolerance in a plant or for increasing the shelf-life of a cut plant. A phytopharmaceutical composition comprising β-cyclocitric acid or a salt thereof.