Beta-Emission 2D Imaging Apparatus for Nuclide Discrimination

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Solution Overview

Problem

Conventional imaging methods, such as imaging plates and photon counting detectors, struggle to distinguish between different nuclides emitting beta rays due to continuous energy spectra and lack of temporal resolution, limiting the ability to perform high-resolution, discriminative imaging of multiple nuclides simultaneously.

Innovation Solution

A beta-emission two-dimensional imaging apparatus comprising a beta ray detector and a gamma ray detector that captures beta rays and peculiar gamma rays emitted by nuclides, allowing for discriminative imaging by correlating the time and location of beta ray detection with the energy of gamma ray emission, enabling the generation of separate distribution images for each nuclide based on their unique gamma ray energies.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional imaging plates or photon counting detectors are used to detect beta rays, then the imaging apparatus can measure the integrated amount of energy or perform event-by-event signal processing, but it cannot distinguish between different nuclides emitting beta rays due to continuous energy spectra

Engineering Contradiction:
Improvenuclide discrimination capabilityVSAvoidenergy and time information of individual radiation events
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The invention segments the detection process into multiple independent detection regions (first detection region and second detection region) positioned at different locations relative to the imaging target. By placing detectors at specific geometries, beta rays from different nuclides can be directed to different detection regions, enabling nuclide discrimination through spatial segmentation rather than energy discrimination.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention transitions from energy-based discrimination (which fails for beta rays with continuous spectra) to spatial-based discrimination. By introducing a spatial dimension through multiple detection regions positioned at different angles and locations, the system can distinguish nuclides based on the directional information of emitted beta rays, effectively adding a new dimension to the detection capability.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Adaptability or versatility

If multiple molecular simultaneous imaging is performed on a PET system, then the distribution of multiple nuclides can be imaged at once, but the system complexity and cost increase significantly

Engineering Contradiction:
Improvemultiple nuclides imaging capabilityVSAvoidsystem configuration complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The invention creates a universal imaging apparatus that can detect multiple types of beta rays (electron-type and positron-type) simultaneously using the same detection system. The apparatus does not require separate specialized systems for different nuclide types, achieving multi-functionality through a unified detection platform that simplifies the overall system architecture.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

Instead of using the conventional PET approach that detects annihilation gamma rays from positron emission, the invention inverts the detection principle by directly detecting beta rays (both electrons and positrons) in their emission direction. This inversion allows simultaneous detection of different beta ray types without requiring complex coincidence detection systems, reducing system complexity.

Inventive Principle:
Principle #13The other way round (Inversion)

3Measurement precision

If photon counting technique is used for beta ray detection, then energy and time of incidence can be calculated event-by-event, but the number of required signal processing circuits increases with the number of imaging elements

Engineering Contradiction:
Improveenergy and time resolutionVSAvoidsignal processing circuit quantity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The invention merges the detection functions for different beta ray types into a single integrated detection system. Instead of requiring separate photon counting circuits for each imaging element to achieve nuclide discrimination, the system combines spatial information from multiple detection regions with a unified signal processing approach, reducing the total number of independent high-complexity circuits required.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention introduces an intermediary spatial dimension (the geometric arrangement of detection regions) that mediates between the beta ray source and the signal processing circuits. This intermediary allows the system to perform nuclide discrimination through spatial positioning rather than requiring complex energy analysis at each imaging element, thereby reducing circuit complexity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for the simultaneous imaging of multiple nuclides with improved resolution, enabling discrimination between different nuclides and enhancing the ability to map their distribution, even when they undergo either positive or negative beta decay.

Implementation Method 1

a beta ray detector configured to receive, from an imaging target containing a first nuclide and a second nuclide, a beta ray based on the first or second nuclide and thereby detect the beta ray

Methodology Applied
Scientific EffectIonization: Ionisation

Implementation Method 2

the first nuclide transiting to an excited state of the daughter nucleus by beta decay and, subsequently to emission of a beta ray by beta decay, transiting to the ground state of the daughter nucleus while emitting a first peculiar gamma ray

Methodology Applied
Scientific EffectGamma ray emission: Radioactive Decay

Data Source

PatentUS11259768B2Apparatus and method for beta-emission two-dimensional imaging
Publication Date: 2022.03.01 RIKEN CO LTD
  • US11259768B2 patent drawing
  • US11259768B2 patent drawing
  • US11259768B2 patent drawing

AI summary

An apparatus for beta-emission two-dimensional imaging including: a beta ray detector configured to receive, from an imaging target containing a first nuclide and a second nuclide, a beta ray based on the first or second nuclide and thereby detect the beta ray, the beta ray detector outputting a beta ray detection signal including location information indicating a detection location of the beta ray on a two-dimensional basis; a gamma ray detector configured to detect a gamma ray, the gamma ray detector detecting the first and second peculiar gamma rays in a discriminable manner; and an imaging processor configured to be capable of generating a distribution image of the first nuclide and a distribution image of the second nuclide in a discriminable manner.