Beta-Glucan Thickener Composition for Cohesive Dysphagia Nutrition

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Solution Overview

Problem

Individuals with dysphagia face challenges in swallowing due to increased viscosity of nutritional products, leading to aspiration, coughing, and choking, with existing thickeners causing undesirable organoleptic properties and lack of cohesiveness, resulting in health complications and high costs.

Innovation Solution

A thickener formulation comprising beta-glucan and additives like gum arabic or carrageenan, providing a relaxation time of over 10 ms, enhancing cohesiveness without significantly increasing viscosity, and promoting safer swallowing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional thickeners (starch or gum) are added to increase shear viscosity, then swallowing safety is improved, but organoleptic properties deteriorate and cohesiveness is lost

Engineering Contradiction:
Improveswallowing safetyVSAvoidorganoleptic properties
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent changes the rheological parameters of the nutritional product by introducing a specific thickening agent composition that modifies both shear viscosity and extensional viscosity in a controlled manner, achieving the desired relaxation time without excessive thickening that would harm organoleptic properties

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses a composite thickening system combining multiple gums (xanthan gum, guar gum, locust bean gum) with specific ratios to achieve synergistic effects that provide both safety and sensory quality, leveraging the complementary properties of each gum type

Inventive Principle:
Principle #40Composite materials

2Reliability

If shear viscosity is increased to prevent aspiration, then swallowing safety is improved, but bolus cohesiveness deteriorates

Engineering Contradiction:
Improveswallowing safetyVSAvoidbolus cohesiveness
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent specifically targets extensional viscosity and relaxation time parameters rather than just shear viscosity, using a thickening agent system that provides appropriate bolus cohesiveness through controlled extensional properties while maintaining safety

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the mechanical thickening approach (starch-based) with a molecular-level thickening mechanism using gum polysaccharides that interact with saliva to provide cohesiveness through molecular entanglement and hydrogen bonding

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If thickener concentration is increased to ensure safety, then swallowing safety is improved, but product cost increases

Engineering Contradiction:
Improveswallowing safetyVSAvoidproduct cost
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent uses a composite gum system where multiple gums work synergistically at lower concentrations to achieve the same or better safety performance, reducing the total amount of thickening agents needed and thereby lowering costs

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent employs cost-effective gum-based thickeners that are more economical than starch-based alternatives, providing a cheaper solution that maintains safety without requiring high concentrations

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation improves swallowing safety and efficiency by preventing residue buildup and reducing aspiration risk, while being more palatable and cost-effective than existing products, allowing individuals to consume a wider variety of foods and beverages.

Implementation Method 1

providing a relaxation time, determined by a Capillary Breakup Extensional Rheometry (CaBER) experiment, of more than 10 ms (milliseconds)

Methodology Applied
Scientific EffectViscoelasticity: Viscoelasticity

Data Source

PatentUS12484605B2Thickeners and nutritional products to promote safe swallowing for individuals with dysphagia and methods of making and using same
Publication Date: 2025.12.02 SOCIETE DES PRODUITS NESTLE SA
  • US12484605B2 patent drawing
  • US12484605B2 patent drawing
  • US12484605B2 patent drawing

AI summary

A thickener is disclosed, as well as a nutritional product including the thickener, uses thereof, methods for the manufacture thereof, methods for improving the cohesiveness of a nutritional product, and related systems. The nutritional products have improved cohesiveness for promoting safer and more efficient swallowing of food boluses for individuals having swallowing difficulties such as dysphagia. In a preferred embodiment, the nutritional product includes a thickener comprising a beta-glucan and an additive. Preferably, the nutritional product has a relaxation time, determined by a Capillary Breakup Extensional Rheometry (CaBER) experiment, of from 10 ms to 2000 ms at a temperature of 20° C.