Low-lead BHB Salt Adsorption Purification

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Solution Overview

Problem

Conventional beta-hydroxybutyrate (BHB) salts contain excessive levels of lead and arsenic, which are harmful to the human body and not effectively controlled, posing health risks due to the accumulation of these heavy metals.

Innovation Solution

A method involving an adsorption process using specific adsorbents and solvents to control and reduce lead and arsenic levels in BHB salts, resulting in low-lead and low-arsenic BHB salts with controlled levels of 10-50 parts per billion, ensuring chemical stability and safety for use as dietary supplements and pharmaceuticals.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If conventional BHB salt production methods are used, then production cost and ease of manufacture are maintained, but lead and arsenic levels remain excessively high causing health risks

Engineering Contradiction:
Improvelead and arsenic levelsVSAvoidmanufacturing process complexity
Core Design Contradiction:
Object-affected harmful factorsVSEase of manufacture

Solution Approach 1:

The patent applies extraction by introducing adsorbent materials (such as activated carbon, ion exchange resins, or chelating agents) that specifically bind and remove lead and arsenic ions from the BHB salt production solution. This separates the harmful heavy metals from the beneficial BHB salt product, achieving low-lead and low-arsenic levels while maintaining a relatively simple manufacturing process

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent uses adsorbent materials as intermediary substances that facilitate the removal of lead and arsenic. These intermediaries (adsorbents) interact with the heavy metal ions in the production solution, capturing them through adsorption or chelation mechanisms, and can be subsequently separated from the purified BHB salt product

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If adsorption process is introduced to reduce heavy metals, then lead and arsenic levels are controlled to safe ranges, but manufacturing process complexity increases

Engineering Contradiction:
Improveheavy metal accumulationVSAvoidadsorption process equipment
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent employs porous adsorbent materials (such as activated carbon with high surface area and porosity, or porous ion exchange resins) that provide extensive surface area for heavy metal adsorption. These porous materials can be added directly to the production solution as powders or granules, allowing effective heavy metal removal through simple mixing and filtration without requiring complex equipment

Inventive Principle:
Principle #31Porous materials

Solution Approach 2:

The patent optimizes adsorption process parameters such as adsorbent dosage, contact time, pH level, and temperature to achieve effective heavy metal removal with minimal process complexity. By adjusting these parameters, the adsorption efficiency is maximized while keeping the manufacturing process simple and cost-effective

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method effectively produces BHB salts with lead and arsenic levels within safe ranges, achieving high purity and yield, making them safer and healthier alternatives to existing BHB salts, suitable for dietary use and pharmaceutical applications.

Implementation Method 1

the preparation process according to the present invention includes an adsorption process (by particular adsorbent(s) and adsorbed solvent) for effectively adsorbing, controlling, and reducing the amounts of heavy metals including lead and arsenic

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentUS20240190803A1Low-lead and low-arsenic beta-hydroxybutyrate salts and methods for producing the same
Publication Date: 2024.06.13 NANJING NUTRABUILDING BIO TECH CO LTD

AI summary

Among others, the present invention provides low-lead and low-arsenic beta-hydroxybutyrate (BHB) salts, comprising lead ranging from 10 to 50 parts per billion (ppb) and arsenic ranging from 10 to 150 ppb. The present invention also provides methods for preparing low-lead and low-arsenic beta-hydroxybutyrate (BHB) salts, which may include (a) synthesizing, (b) adsorbing (e.g., by adsorbent and solvent), (c) concentrating under reduced pressure, and (d) spray drying.