Bicarbonate Ringer's Solution Anesthesia Arousal
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current methods for awakening patients from general anesthesia are challenging to control and often require experienced anesthesiologists, leading to delayed recovery and increased risk of complications due to prolonged metabolic and respiratory suppression.
Innovation Solution
A bicarbonate ion-containing anesthesia arousal composition, specifically a Ringer's solution with sodium bicarbonate as a major component, is administered to perioperative patients to facilitate early awakening by correcting acidosis and maintaining normal blood pH, thereby increasing protein binding of anesthetics and reducing the need for expert anesthesiological control.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If general anesthesia is administered to suppress central nervous system activity during surgery, then surgical conditions are improved, but awakening time is delayed and metabolic recovery is slowed
Solution Approach 1:
The patent applies preliminary action by administering a bicarbonate ion-containing composition before or during the end of anesthesia to proactively accelerate awakening. The bicarbonate ions are introduced in advance to correct acidosis and promote anesthetic elimination, rather than waiting for natural recovery processes.
Solution Approach 2:
The patent changes the chemical parameter of blood pH by introducing bicarbonate ions, which act as a buffer to correct acidosis. This parameter change (increasing pH) directly affects the protein binding of anesthetic drugs, reducing their effect and accelerating awakening from anesthesia.
2Loss of time
If experienced anesthesiologists control anesthesia administration rate, then awakening can be facilitated, but device complexity and operational skill requirements increase
Solution Approach 1:
The patent applies self-service by using the bicarbonate ion-containing composition to automatically correct acidosis and facilitate awakening without requiring continuous expert intervention. The chemical agent works autonomously to improve metabolic conditions and accelerate anesthetic elimination, reducing dependence on anesthesiologist expertise.
3Reliability
If delayed awakening from anesthesia occurs, then ICU care requirements and medical staff workload increase
Solution Approach 1:
The patent applies preliminary action by administering bicarbonate ions to proactively prevent delayed awakening and reduce the need for extended ICU care. The composition is given before awakening naturally occurs to ensure faster metabolic recovery and reduce subsequent medical intervention requirements.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The bicarbonate ion-containing Ringer's solution accelerates postoperative awakening, reduces ICU care requirements, and decreases the workload for medical staff by enabling stable, early awakening from general anesthesia without relying on anesthesiological expertise, thus minimizing complications related to delayed recovery.
Implementation Method 1
a bicarbonate ion-containing anesthesia arousal composition, specifically a Ringer's solution with sodium bicarbonate as a major component, is administered to perioperative patients to facilitate early awakening by correcting acidosis and maintaining normal blood pH
Data Source
Figure 1
AI summary
A method for facilitating postoperative awakening of patients from anesthesia does not depend on the experience of anesthesiologists. Also provided are an anesthesia arousal composition for use in this method and a preparation containing a bicarbonate ion that facilitates awakening from anesthesia. Specifically, the anesthesia arousal composition is provided in the form of infusion fluid. The method for controlling and facilitating awakening from anesthesia involves administering the anesthesia arousal composition. The present invention preferably provides an anesthesia arousal composition or an acidosis-correcting composition containing sodium bicarbonate as a major component that serves as a source of the bicarbonate ion, along with each or a combination of another electrolyte, glucose and an amino acid.