Substituted Bicyclic Compounds for Broad-Spectrum Pesticidal Control
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Solution Overview
Problem
There is a need for new compounds with high pesticidal activity and a broad spectrum of activity against invertebrate pests, such as insects, arachnids, and nematodes, due to the development of resistance to existing agents and the difficulty in controlling these pests effectively.
Innovation Solution
Substituted bicyclic compounds of formula I, including their stereoisomers, salts, tautomers, and N-oxides, are developed for use as agrochemical pesticides, which are synthesized through various modification procedures and can be applied in agricultural or veterinary compositions to combat invertebrate pests.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing pesticidal agents are used, then initial pesticidal activity is achieved, but resistance develops reducing effectiveness over time
Solution Approach 1:
The patent applies parameter changes by developing new chemical compounds with modified molecular structures (formula I bicyclic compounds with specific substituents) that differ from existing pesticidal agents. This structural parameter change creates new modes of action that pests have not developed resistance against, thereby maintaining long-term effectiveness while preserving initial high activity.
2Adaptability or versatility
If new pesticidal compounds are developed, then activity spectrum is expanded, but development complexity increases
Solution Approach 1:
The patent achieves universality by designing a core bicyclic compound structure (formula I) that can serve multiple pesticidal functions against different invertebrate pest types including insects, arachnids, and nematodes. The core structure provides broad-spectrum activity while systematic substitution patterns allow optimization for specific target pests, balancing versatility with manageable structural complexity.
3Adaptability or versatility
If compound synthesis procedures are expanded, then compound diversity increases, but manufacturing complexity increases
Solution Approach 1:
The patent applies segmentation by dividing the molecule into a core bicyclic structure (formula I) and various substituent groups (R1, R2, R3, Rx, Ar, Het). This segmentation allows independent optimization of each component and enables systematic synthesis through modular assembly of building blocks, thereby increasing compound diversity while maintaining manageable manufacturing complexity through standardized synthetic pathways.
Data Source
AI summary
The present invention relates to compounds of formula I,wherein the variables are defined as given in the description and claims. The invention further relates to uses, processes and composition for compounds I.