Bidirectional Infusion Liquid Conditioning to Reduce Site Inflammation

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Solution Overview

Problem

Conventional infusion devices face challenges in maintaining infusion site viability due to infusion liquid degradation, inflammation, and scarring, which can be exacerbated by preservatives and unpredictable storage conditions.

Innovation Solution

A transferring and conditioning device with a flowpath and conditioner that preferentially directs liquid flow through separate passages, utilizing a check valve and multiple conditioning stages to remove impurities and additives, and add beneficial substances, thereby prolonging infusion site viability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If infusion liquid is stored and transferred using conventional methods, then the liquid can be delivered to the patient, but the infusion site viability deteriorates due to liquid degradation, inflammation, and scarring

Engineering Contradiction:
Improveinfusion site viabilityVSAvoidinflammation and scarring
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The device performs preliminary conditioning of the infusion liquid before it contacts the infusion site. The conditioner modifies the liquid properties in advance by removing harmful preservatives and additives, and by adding beneficial substances, so that when the liquid is infused, it does not cause inflammation or scarring at the infusion site.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The conditioner acts as an intermediary device between the infusion liquid storage and the infusion site. It processes the liquid through a flowpath with passages that enable conditioning operations, serving as a mediator that modifies the liquid to protect the infusion site from harmful effects while maintaining therapeutic efficacy.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If a single flowpath is used for liquid transfer, then the device structure is simple, but the liquid cannot be effectively conditioned without affecting flow direction

Engineering Contradiction:
Improveflowpath structureVSAvoidliquid conditioning effectiveness
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The flowpath is segmented into multiple passages within the conditioner, including a first passage and a second passage. This segmentation allows the liquid to be directed through different paths depending on the desired operation - one passage enables removal of harmful substances while another facilitates addition of beneficial substances, achieving effective conditioning without compromising structural simplicity.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device extends infusion site longevity by reducing inflammation and scarring, maintaining infusion efficacy, and minimizing the need for frequent site changes, thus enhancing patient convenience and reducing waste.

Implementation Method 1

a check valve at the second passage. The check valve is configured to cause liquid moving between the port and the container in a first direction to move preferentially via the first passage. The check valve is also configured to cause liquid moving between the port and the container in a second direction to move preferentially via the second passage

Methodology Applied
Scientific EffectCheck valve mechanism: Valve

Data Source

PatentUS12491314B2Device for transferring and conditioning infusion liquid and related technology
Publication Date: 2025.12.09 MEDTRONIC MINIMED INC
  • US12491314B2 patent drawing
  • US12491314B2 patent drawing
  • US12491314B2 patent drawing

AI summary

A device in accordance with an embodiment of the present technology includes a port through which the device receives and dispenses infusion liquid (e.g., insulin solution) and a container that holds the infusion liquid. The device also includes a hub at a flowpath extending between the port and the container. The hub defines a first passage and a second passage in parallel with one another. The device further includes a conditioner and a check valve at the first and second passages, respectively. The conditioner conditions liquid moving between the container and the port by passing the liquid through an adsorbent filter and a mechanical filter. The check valve causes liquid moving between the port and the container to move preferentially via the first passage when flowing in one direction and to move preferentially via the second passage when flowing in an opposite direction.