Bidirectional Neuron Probe with Integrated Sensor Array

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Solution Overview

Problem

Current medical devices for neuromuscular and neuromodulation stimulation lack the ability to simultaneously monitor and stimulate signals effectively, with limitations in signal sensitivity, portability, treatment regimens, and usability, particularly for implantable devices which face challenges in size and cost.

Innovation Solution

Development of biocompatible, compact medical devices equipped with probes and sensors capable of monitoring ultra-low magnetic signals, allowing for both implantable and external use, featuring a differential configuration of sensors to enhance signal processing and reduce noise, along with electrical pulse generators for stimulation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If medical devices use traditional sensors for signal monitoring, then device size can be reduced, but signal sensitivity and detection precision deteriorate

Engineering Contradiction:
Improvesignal sensitivityVSAvoiddevice size
Core Design Contradiction:
Measurement precisionVSVolume of moving object

Solution Approach 1:

The patent combines multiple sensors (magnetometer, accelerometer, gyroscope) into an integrated sensor array within the implantable device. This merging approach allows the device to detect ultra-low magnetic signals with high sensitivity while maintaining a compact form factor suitable for implantation, resolving the contradiction between signal detection precision and device size

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The sensor array is designed to perform multiple functions: detecting magnetic fields generated by neuronal activity, monitoring acceleration and orientation, and providing spatial reference information. This multi-functionality allows a single integrated sensor system to achieve high measurement precision across multiple parameters without proportionally increasing device volume

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Ease of operation

If medical devices are designed as implantable probes, then portability and usability are improved, but manufacturing complexity and cost increase

Engineering Contradiction:
ImproveportabilityVSAvoidmanufacturing complexity
Core Design Contradiction:
Ease of operationVSEase of manufacture

Solution Approach 1:

The implantable device is segmented into distinct functional modules: a sensor array for signal detection, a stimulator for electrical stimulation, and a signal processing unit. This modular segmentation simplifies manufacturing by allowing each module to be optimized and tested independently before final assembly, reducing overall manufacturing complexity while maintaining portability

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs a nested structure where the sensor array and stimulator are integrated within a compact implantable probe housing. The sensor array is positioned at the tip of the probe, with processing electronics nested within the body of the device. This nesting approach minimizes the overall device volume for implantation while managing the complexity of integrating multiple functions in a small form factor

Inventive Principle:
Principle #7Nested doll (Nesting)

3Adaptability or versatility

If devices monitor and stimulate signals simultaneously, then treatment effectiveness is improved, but device complexity increases

Engineering Contradiction:
Improvebidirectional functionalityVSAvoiddevice complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent merges the monitoring and stimulation functions into a single integrated device platform. The sensor array detects neuronal signals while the stimulator delivers electrical stimulation through the same implantable probe. This combining of bidirectional functions into one device reduces the need for multiple separate implants, managing system complexity while providing comprehensive monitoring and treatment capabilities

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device implements feedback control where signals detected by the sensor array are processed and used to control the stimulation output. The signal processing unit analyzes detected neuronal activity and adjusts stimulation parameters in real-time. This feedback mechanism enables adaptive bidirectional operation, improving treatment effectiveness while managing complexity through automated control algorithms rather than requiring complex manual coordination of separate monitoring and stimulation systems

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution enables effective monitoring and stimulation of electrically excitable cells, improving signal detection and reducing noise, thereby enhancing the diagnostic and therapeutic capabilities for conditions related to signal transmission malfunctions.

Implementation Method 1

at least one sensor or sensor array adapted for monitoring a signal; wherein the signal monitored by the at least one sensor or sensor array is a magnetic signal

Methodology Applied
Scientific EffectMagnetic field sensing: Magnetic Field

Data Source

PatentEP3939497A1Bidirectional medical devices for monitoring and stimulating neurons
Publication Date: 2022.01.19 FUNDACION IMDEA NANOCIENCIA
  • EP3939497A1 patent drawingFigure 1(a)~2
  • EP3939497A1 patent drawingFigure 3~4(d)
  • EP3939497A1 patent drawingFigure 5~6(c)

AI summary

The present invention relates to a probe, a monitoring device, a method for monitoring, the use of the monitoring device, a medical device A, a medical device B, methods for cell monitoring and stimulating, the use of medical device A and the use of medical device B.