Bifidobacterium Lysate for Sensitive Skin Neurotransmitter Inhibition
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current treatments for sensitive skin disorders are inadequate in addressing the discomfort and visible signs associated with sensitive skin, which is distinct from allergic skin and often exacerbated by daily activities and environmental factors.
Innovation Solution
A lysate formed from the intracellular biological constituents and cell wall constituents of Bifidobacterium species microorganisms is used topically to inhibit the release of neurotransmitters and soothe sensory neurons, reducing discomfort and visible signs in sensitive skin.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional treatments for sensitive skin are used, then some skin disorders can be managed, but the discomfort and visible signs associated with sensitive skin remain inadequately addressed
Solution Approach 1:
The patent changes the fundamental parameter of the treatment agent from conventional skincare ingredients to a microbial lysate composed of intracellular biological constituents and cell wall constituents of Bifidobacterium species. This parameter change enables the treatment to specifically target and modulate sensory neuron activity and neurotransmitter release, thereby effectively reducing skin discomfort and reactivity that conventional treatments cannot adequately address
Solution Approach 2:
The Bifidobacterium lysate acts as an intermediary substance that mediates between the skin's sensory neurons and external irritants. By inhibiting neurotransmitter release from sensory neurons, the lysate prevents the transmission of discomfort signals to the brain, providing relief from dysesthetic sensations without requiring immunological or anti-inflammatory mechanisms
2Adaptability or versatility
If probiotic microorganisms are used to regulate cutaneous hypersensitivity reactions, then immunological processes can be influenced, but sensitive skin reactions (non-immunological) are not effectively treated
Solution Approach 1:
The patent extracts the active therapeutic components from the probiotic Bifidobacterium species by creating a lysate from intracellular biological constituents and cell wall constituents. This extraction process isolates the bioactive molecules responsible for inhibiting neurotransmitter release and soothing sensory neurons, enabling effective treatment of sensitive skin reactions that are not mediated by immunological processes
Solution Approach 2:
The patent changes the form of the probiotic from live microorganisms to a lysate composition containing intracellular and cell wall constituents. This parameter change allows the treatment to function through direct inhibition of neurotransmitter release from sensory neurons, making it effective for non-immunological sensitive skin reactions while maintaining safety and stability
Data Source
AI summary
The present invention relates to the cosmetic use of an effective amount of at least one lysate of at least one microorganism of the genus Bifidobacterium species and/or fraction thereof to prevent and/or treat a skin disorder in sensitive skin.