Bilayer Sleep Caplet with Segmented Release Layers

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Solution Overview

Problem

Current sleep aids often lead to negative side effects such as dependence, impaired cognitive function, and disruption of REM sleep, while failing to effectively address sleep quality and duration issues.

Innovation Solution

A customized bilayer caplet with an immediate release layer containing L-Theanine, Skullcap Herb, Rhodiola, and Chamomile, and a time release melatonin layer, designed to promote relaxation, induce sleep, and maintain sleep through a three-phase approach, avoiding the negative effects of traditional sleep aids.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If traditional sleep aids (benzodiazepines, Z-drugs) are used to induce sleep, then sleep onset is improved, but dependence and side effects occur

Engineering Contradiction:
Improvesleep onset speedVSAvoiddependence risk
Core Design Contradiction:
SpeedVSReliability

Solution Approach 1:

The patent divides the sleep aid into two distinct layers: an immediate-release layer containing herbal ingredients (L-Theanine, Skullcap, Rhodiola, Chamomile) for rapid relaxation effect, and a time-release layer containing melatonin for sustained sleep maintenance. This segmentation allows different mechanisms to work at different times, achieving fast sleep onset without the dependence risks of traditional hypnotics.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention combines multiple natural ingredients with complementary mechanisms of action: GABAergic herbs (L-Theanine, Skullcap, Chamomile) for immediate relaxation, adaptogenic Rhodiola for stress reduction, and melatonin for circadian rhythm regulation. This composite approach creates a synergistic effect that addresses sleep onset and maintenance while avoiding dependence.

Inventive Principle:
Principle #40Composite materials

2Duration of action of moving object

If traditional sleep aids are used to increase slow-wave sleep, then sleep duration is improved, but REM sleep is disrupted

Engineering Contradiction:
Improvesleep durationVSAvoidsleep stage balance
Core Design Contradiction:
Duration of action of moving objectVSStability of the object's composition

Solution Approach 1:

The bilayer structure separates the functions of sleep induction and sleep maintenance. The immediate-release herbal layer facilitates rapid transition to sleep without suppressing REM sleep, while the time-release melatonin layer maintains sleep duration and supports natural sleep stage cycling, including preserved REM sleep architecture.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent changes the release parameter of melatonin from immediate to time-release formulation, creating a gradual concentration profile that maintains therapeutic levels throughout the night. This parameter change allows sustained sleep duration while avoiding the abrupt suppression of natural sleep stage transitions that occurs with traditional hypnotics.

Inventive Principle:
Principle #35Parameter changes

3Speed

If immediate release of all ingredients is used, then rapid sleep induction is achieved, but sleep maintenance is insufficient

Engineering Contradiction:
Improvesleep induction speedVSAvoidsleep maintenance duration
Core Design Contradiction:
SpeedVSDuration of action of moving object

Solution Approach 1:

The patent segments the dosage form into two layers with different release characteristics. The immediate-release layer provides rapid onset of relaxation effects within minutes, while the time-release melatonin layer provides sustained release over 6-8 hours to maintain sleep through the night, addressing both speed and duration requirements.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The immediate-release herbal layer performs preliminary relaxation and anxiety reduction before the full effect of melatonin takes hold. This preliminary action prepares the user for sleep onset, while the subsequent time-release melatonin maintains sleep continuity, creating a coordinated two-phase approach.

Inventive Principle:
Principle #10Preliminary action

4Speed

If high doses of melatonin are released immediately, then sleep induction is enhanced, but sleep quality deteriorates due to disrupted sleep stages

Engineering Contradiction:
Improvesleep induction enhancementVSAvoidsleep stage quality
Core Design Contradiction:
SpeedVSStability of the object's composition

Solution Approach 1:

The patent changes the release parameter of melatonin from immediate to time-release, creating a controlled concentration profile that avoids peak-related disruptions to sleep architecture. The gradual release maintains therapeutic levels throughout the night without the abrupt peaks that can suppress REM sleep and disrupt natural cycling, thereby preserving sleep quality.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS10568856B2Composition for improved sleep
Publication Date: 2020.02.25 JAMIESON LAB

AI summary

Compositions are disclosed for improved sleep quality and quantity including ingredients for both immediate release and controlled release. The invention provides improved supplemental compositions, and methods for administering same to a user, for enhancing the onset, quality, and duration of sleep in humans and animals. The supplemental composition may contain a combination of ingredients in proportions calculated to relieve stress, promote relaxation, and enhance sleep, including at least the following ingredients: L-Theanine, Skullcap Herb (Scutellaria lateriflora L.), Rhodiola (Rhodiola rosea L.), and Chamomile Flower (Matricaria Recutita). In addition, the supplemental composition may include the secondary ingredient Melatonin. The selection and amounts of the ingredients of the supplemental composition promote sleep onset, quality, and duration and may be provided for consumption at least one time daily, e.g., prior to sleep. The composition may be in a layered solid dosage form to provide controlled and sustained release of specific ingredients.