Bilirubin Sensor Segmentation for Continuous Monitoring

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Solution Overview

Problem

Conventional bilirubin concentration measurement systems using optical methods are large and cumbersome, making it difficult to continuously monitor bilirubin levels in newborns and infants, whose concentrations can change rapidly.

Innovation Solution

A compact bilirubin concentration measurement system comprising a sensor device attachable to a subject, equipped with light emitting elements emitting light in different wavelength bands and a light detection element, which wirelessly transmits intensity data to a terminal device for calculation and display, allowing continuous monitoring.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If conventional optical bilirubin measurement apparatuses are used, then bilirubin concentration can be measured non-invasively, but the apparatuses are large in size and cannot achieve continuous monitoring

Engineering Contradiction:
Improvenon-invasive measurementVSAvoidapparatus size
Core Design Contradiction:
Ease of operationVSVolume of moving object

Solution Approach 1:

The invention divides the measurement system into two independent parts: a compact sensor device that can be attached to the subject for continuous monitoring, and a separate terminal device that processes data and displays results. This segmentation allows the sensor device to be small and portable while the terminal device handles the computational tasks, resolving the contradiction between compact size and measurement capability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces wireless communication as an intermediary between the sensor device and terminal device. This allows data transmission without physical connections, enabling the sensor device to remain compact and portable while maintaining full measurement and communication functionality, thus resolving the size constraint.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If conventional optical bilirubin measurement apparatuses are used, then bilirubin concentration can be measured, but medical staff must conduct measurements manually at every time point, making continuous monitoring difficult

Engineering Contradiction:
Improvebilirubin concentration measurementVSAvoidmanual measurement operation
Core Design Contradiction:
Measurement precisionVSExtent of automation

Solution Approach 1:

The sensor device is designed to autonomously perform measurements and wirelessly transmit data to the terminal device without requiring manual intervention. The system automatically calculates bilirubin concentration and continuously monitors changes, enabling self-service operation that resolves the contradiction between measurement precision and automation.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The invention enables continuous monitoring by having the sensor device continuously measure bilirubin concentration and transmit data in real-time. This continuous action eliminates the need for discrete manual measurements at scheduled intervals, allowing the system to track rapid changes in bilirubin levels automatically.

Inventive Principle:
Principle #20Continuity of useful action

3Measurement precision

If blood sampling method is used, then bilirubin values can be highly accurately measured, but the method is invasive and requires time and effort

Engineering Contradiction:
Improvebilirubin measurement accuracyVSAvoidinvasive procedure complexity
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent replaces the mechanical blood sampling process with an optical measurement system. The sensor device uses light emission and detection to measure bilirubin concentration non-invasively, substituting the mechanical needle insertion and blood collection process with optical fields, thereby eliminating invasiveness while maintaining measurement accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enables continuous, non-invasive, and accurate monitoring of bilirubin concentrations, reducing the burden on medical staff and improving detection of rapid changes in bilirubin levels.

Implementation Method 1

a first light emitting element that emits light in a first wavelength band at a first timing; a second light emitting element that emits light in a second wavelength band at a second timing

Methodology Applied
Scientific EffectLight emission: Light Emitting Diode

Implementation Method 2

a light detection element that detects first reflected light that is the light in the first wavelength band having been incident on skin of the subject and been reflected at the first timing, and detects second reflected light that is the light in the second wavelength band having been incident on the skin of the subject and been reflected at the second timing

Methodology Applied
Scientific EffectLight reflection: Reflection

Data Source

PatentUS12178573B2Bilirubin concentration measurement system
Publication Date: 2024.12.31 NAT UNIV CORP YOKOHAMA NAT UNIV
  • US12178573B2 patent drawing
  • US12178573B2 patent drawing
  • US12178573B2 patent drawing

AI summary

A bilirubin concentration measurement system including: a sensor device attachable to a subject; and a terminal device capable of wirelessly communicating with the sensor device. The sensor device includes: a light emitting diode that emits blue light; a light emitting diode that emits green light; a light detection diode that detects reflected light that is the blue light having been incident on skin of the subject and reflected, and detects reflected light that is the green light having been incident on the skin of the subject and reflected; and a communication unit that wirelessly transmits information about intensities of the reflected light detected by the photodiode. The terminal device includes: a communication unit that receives the information about the intensities of the reflected light transmitted from the sensor device; and a computing unit that calculates a bilirubin concentration using the information about the intensities of the reflected light.