Bioactive Composite Coating for Implant Bone Attachment

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Solution Overview

Problem

Current methods for attaching metallic implants to bone, such as hip and knee prostheses, lack long-term stability and effective adhesion, with existing surface roughening and bioactive materials not fully addressing the need for reliable attachment and antimicrobial properties.

Innovation Solution

A method involving surface abrasion followed by a composite structure coating with fibre fabrics and bioactive particles, where the mesh size of the second fibre fabric is smaller than the bioactive particles, allowing for enhanced adhesion, mechanical interlocking, and bone ingrowth, while maintaining load-bearing capabilities.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If bone cement or press-fit methods are used to attach metallic implants to bone, then the implant can be installed, but long-term stability and reliable attachment are not achieved

Engineering Contradiction:
Improveattachment stabilityVSAvoidlong-term stability
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent applies composite materials by combining fibre-reinforced resin structures with bioactive glass particles on the implant surface. The composite comprises fibres (glass, carbon, or organic) embedded in a resin matrix, with bioactive particles distributed throughout, creating a multi-phase material that provides both mechanical strength for load-bearing and bioactivity for bone attachment.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent utilizes porous materials by creating a porous coating structure with interconnected voids and channels within the fibre-reinforced resin composite. This porous architecture allows bone ingrowth into the coating, providing biological fixation while maintaining mechanical integrity. The porosity enables osteoconduction and vascularization, directly addressing the long-term stability requirement.

Inventive Principle:
Principle #31Porous materials

2Reliability

If surface roughening is applied to enhance bone attachment, then adhesion is improved, but antimicrobial properties are not provided

Engineering Contradiction:
ImproveadhesionVSAvoidmicrobial infection
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent combines adhesion-enhancing surface roughening with antimicrobial bioactive particles in a composite coating structure. The fibres and resin matrix provide mechanical interlocking and adhesion, while the bioactive glass particles deliver antimicrobial functionality, simultaneously addressing both adhesion and infection prevention requirements.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The coating is designed with multi-functionality by integrating multiple roles into a single composite structure: mechanical adhesion through fibre-reinforced resin, bone attachment through bioactive particles, antimicrobial protection through bioactive glass, and load-bearing capacity through the fibre network. This universal coating addresses multiple requirements simultaneously.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If a composite coating with fibre bundles and bioactive particles is applied, then adhesion and bone attachment are enhanced, but the device complexity increases

Engineering Contradiction:
Improveattachment to boneVSAvoidcoating structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by pre-impregnating fibres with resin and pre-distributing bioactive particles within the coating matrix before applying the composite to the implant surface. The fibres are pre-coated with resin to ensure proper adhesion, and bioactive particles are pre-mixed into the resin-fibre composite, simplifying the application process despite the complex final structure.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The resin matrix serves as an intermediary that binds the fibres together and incorporates the bioactive particles, creating a unified composite coating. The resin mediates between the structural fibres and the functional bioactive particles, enabling their integration into a cohesive coating system that can be applied as a single layer.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Reliability

If the mesh size of the second fibre fabric is smaller than the bioactive particles, then particle retention is improved, but manufacturing precision requirements increase

Engineering Contradiction:
Improveparticle retentionVSAvoidmesh size control
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent applies parameter changes by carefully controlling the mesh size parameter of the second fibre fabric to be smaller than the bioactive particles. This parameter relationship ensures that particles are retained within the coating structure while allowing the fabric to provide structural support. The mesh size is selected as a critical parameter to balance particle retention with manufacturing feasibility.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method provides a biologically and mechanically compatible coating that enhances adhesion and attachment to bone, reducing the need for frequent implant replacement and improving patient quality of life and healthcare costs by ensuring long-term stability and antimicrobial effects.

Implementation Method 1

a first fibre fabric impregnated with a first resin... arranged in contact with the abraded surface

Methodology Applied
Scientific EffectAdhesion: Adhesive

Implementation Method 2

polymerising the resins of the composite structure

Methodology Applied
Scientific EffectPolymerisation: Photopolymerisation

Implementation Method 3

abrading the surface to be coated with particles to form an abraded surface

Methodology Applied
Scientific EffectAbrasion: Abrasion

Implementation Method 4

particles of bioactive material arranged into said in-between spaces of the fibre bundle and arranged in contact with the first fibre fabric

Methodology Applied
Scientific EffectBioactive material deposition: Deposition (physical)

Data Source

PatentEP2853384B1A method for coating and a coated surface
Publication Date: 2016.11.23 SKULLE IMPLANTS
  • EP2853384B1 patent drawingFigure 1
  • EP2853384B1 patent drawingFigure 2a~2b
  • EP2853384B1 patent drawingFigure 3

AI summary

A method of coating a surface according to the present invention comprises the steps of abrading the surface to be coated with particles, then arranging a composite structure comprising a layer fibre fabric, a fibre bundle applied according to a pattern and particles of bioactive material in between the fibre bundle's pattern, and a second fibre fabric. The method and coated implants manufactured by the method provide implants with good load bearing capabilities for use for example in hip implants.