Bioadhesive Polymer Particles for Bacterial Adhesion Control

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Solution Overview

Problem

Current methods for preventing tooth decay and bacterial attachment to oral surfaces require regular plaque removal or the application of contiguous polymer layers, which are not always practical or effective without professional intervention.

Innovation Solution

Development of particles comprising a core, such as silicon oxide or zinc oxide, conjugated with bioadhesive polymers like polysaccharides, which disrupt bacterial attachment to oral surfaces, inhibiting biofilm formation and reducing the risk of dental caries and periodontal diseases.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If regular plaque removal is performed, then bacterial attachment is controlled, but it requires frequent manual intervention and professional dental visits

Engineering Contradiction:
Improvebacterial attachment controlVSAvoidfrequency of intervention
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-coating the tooth surface with a bioadhesive polymer layer that provides long-term anti-bacterial protection. This preliminary protective layer remains on the tooth surface for extended periods, reducing the need for frequent manual plaque removal and professional dental visits while maintaining reliable bacterial attachment control.

Inventive Principle:
Principle #10Preliminary action

2Reliability

If contiguous polymer sealants are applied, then bacterial contact with tooth surface is prevented, but it requires professional dental intervention and creates a continuous coating

Engineering Contradiction:
Improvebacterial contact preventionVSAvoidapplication requirement
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent applies segmentation by using discrete particles containing anti-bacterial agents instead of a continuous polymer sealant. These particles are distributed across the tooth surface and provide localized protection, eliminating the need for professional application of continuous coatings while maintaining effective bacterial contact prevention.

Inventive Principle:
Principle #1Segmentation

3Reliability

If anti-bacterial agents are included in dental compositions, then bacterial propagation is inhibited temporarily, but it requires repeated application and does not prevent initial attachment

Engineering Contradiction:
Improvebacterial propagation inhibitionVSAvoidresidual effect duration
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent applies preliminary action by preventing bacterial attachment in the first place through the bioadhesive polymer barrier, rather than merely inhibiting propagation after attachment occurs. This preliminary prevention mechanism provides long-lasting protection without requiring repeated applications, addressing both the reliability and duration limitations of conventional anti-bacterial agents.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The particles effectively prevent bacterial attachment and biofilm formation on teeth and gums without the need for continuous polymer layers or professional intervention, providing a long-lasting solution to tooth decay and oral health issues.

Implementation Method 1

The particle includes (i) a core that has an oxide compound or salt and (ii) a bioadhesive polymer. The bioadhesive polymer is attached to the oxide compound or salt.

Methodology Applied
Scientific EffectAdhesion: Adhesive

Implementation Method 2

Particles that disrupt or impede bacterial adhesion... The particles effectively prevent bacterial attachment and biofilm formation on teeth and gums

Methodology Applied
Scientific EffectAdhesion disruption: Adhesive

Data Source

PatentUS8119162B2Particles that disrupt or impede bacterial adhesion, related compositions and methods
Publication Date: 2012.02.21 COLGATE PALMOLIVE CO
  • US8119162B2 patent drawing
  • US8119162B2 patent drawing
  • US8119162B2 patent drawing

AI summary

Oral care and other compositions comprising particles having cores attached to bioadhesive polymers for inhibition of pellicle formation, plaque formation, biofilm formation, biofouling, and microbial adhesion or attachment are described. Methods using said compositions to treat surfaces, such as oral surfaces.