Bioaerosol Sampler With Moisture Exchange Partition

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Solution Overview

Problem

Current bioaerosol sampling methods face challenges in maintaining the viability of collected microorganisms due to desiccation, limited sampling time, and compatibility with analysis techniques, particularly for biological particles like bacteria, viruses, and fungi, as existing methods often result in the death of organisms during collection and storage.

Innovation Solution

The development of an aerosol collection system that includes a bio-aerosol delivery device, a moisture exchange device to humidify or dehumidify the particles, and a nanofiber collection medium that maintains relative humidity and temperature conditions to preserve the viability of collected bioparticles, allowing for extended sampling and storage of viable microorganisms.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional bioaerosol sampling methods are used, then sampling can be performed with simple equipment, but the collected microorganisms die due to desiccation and limited sampling time

Engineering Contradiction:
Improveviability of collected microorganismsVSAvoidsampling time
Core Design Contradiction:
ReliabilityVSDuration of action of moving object

Solution Approach 1:

A moisture exchange device with a partition member is introduced as an intermediary between the air stream and the collection medium. This partition allows water vapor to pass through while blocking liquid water and microorganisms, maintaining humidity on the collection medium to preserve microbial viability during extended sampling periods

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The relative humidity of the collection medium is controlled and maintained within a specific range (e.g., 50-90% RH) by adjusting the moisture exchange rate through the partition member. This parameter control prevents desiccation of collected microorganisms while allowing extended sampling times

Inventive Principle:
Principle #35Parameter changes

2Reliability

If moisture is added to preserve microorganism viability, then sampling time can be extended, but the system complexity increases with additional moisture control devices

Engineering Contradiction:
Improveviability of collected microorganismsVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The partition member structure enables passive moisture exchange where water vapor automatically migrates from the humidified air stream to the collection medium through the partition's micropores, eliminating the need for active humidification systems or complex moisture control mechanisms

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The partition member is constructed as a thin film or membrane with controlled porosity that allows vapor transmission while maintaining structural simplicity. This thin-film approach achieves moisture control without requiring bulky equipment or complex mechanical systems

Inventive Principle:
Principle #30Flexible shells and thin films

3Quantity of substance

If extended sampling is performed to collect sufficient bioaerosols, then sample quantity increases, but microorganism viability is lost due to desiccation

Engineering Contradiction:
Improveamount of collected bioparticlesVSAvoidviability of collected microorganisms
Core Design Contradiction:
Quantity of substanceVSReliability

Solution Approach 1:

The moisture exchange device maintains continuous humidity control throughout the extended sampling period. Water vapor continuously passes through the partition member to replenish moisture on the collection medium, ensuring uninterrupted preservation of microbial viability while sampling continues for extended durations

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The collection medium is pre-humidified before sampling begins, and the moisture exchange system is pre-configured to maintain optimal humidity levels. This preliminary preparation ensures that microorganisms remain viable from the moment of collection throughout extended sampling periods

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively maintains the viability of collected bioparticles for extended periods, enabling longer sampling times and improved storage conditions, enhancing the capability to recover and analyze bioaerosols without significant loss of viability.

Implementation Method 1

a moisture exchange device including a partition member coupled to the gas stream and configured to humidify or dehumidify the bioparticles in the gas stream

Methodology Applied
Scientific EffectHumidification: Evaporation

Implementation Method 2

an aerosol collection medium downstream from the moisture exchange device and configured to collect the bioparticles

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 3

a moisture exchange device including a partition member coupled to the gas stream and configured to humidify or dehumidify the bioparticles in the gas stream

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Data Source

PatentUS10876145B2Fiber sampler for recovery of bioaerosols and particles
Publication Date: 2020.12.29 RES TRIANGLE INST
  • US10876145B2 patent drawing
  • US10876145B2 patent drawing
  • US10876145B2 patent drawing

AI summary

An aerosol collection system and method. The system includes a bio-aerosol delivery device configured to supply bioparticles in a gas stream, a moisture exchange device including a partition member coupled to the gas stream and configured to humidify or dehumidify the bioparticles in the gas stream, and an aerosol collection medium downstream from the moisture exchange device and configured to collect the bioparticles. The method includes delivering bioparticles in a gas stream, humidifying or dehumidifying the bioparticles in the gas stream by transport of water across a partition member and into a vapor phase of the gas stream, and collecting the bioparticles by a collection medium.