Multi-analysis device and method
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Solution Overview
Problem
Current biological sample analysis methods require multiple machines, trained staff, and are time-consuming, leading to delayed diagnoses due to sample preparation and aggregation of results, which can degrade the sample.
Innovation Solution
A multi-analysis device that integrates electroanalytical sensors, lighting modules, and optical sensors within a single container, allowing simultaneous measurement of multiple parameters without sample preparation, using visible, near-infrared, and autofluorescence spectrometry.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If multiple machines are used to measure different parameters, then measurement precision is improved, but device complexity and time consumption increase
Solution Approach 1:
The patent combines multiple measurement techniques (optical sensors for visible/NIR/autofluorescence spectrometry and electroanalytical sensors for electrical properties) into a single integrated analyzing device. This merging allows simultaneous measurement of multiple parameters including absorbance, fluorescence, and electrical conductivity, thereby maintaining measurement precision while reducing device complexity and eliminating the need for multiple separate machines
Solution Approach 2:
The analyzing device is designed with multi-functionality to perform various measurement techniques using a single device. The device can measure optical properties (absorbance, fluorescence) and electrical properties (conductivity, impedance) simultaneously, making it a universal instrument that replaces multiple specialized machines while maintaining the precision of each individual measurement technique
2Measurement precision
If sample preparation and separation into multiple tubes is performed, then measurement accuracy is improved, but loss of time and sample deterioration increase
Solution Approach 1:
The device merges multiple measurement capabilities into a single analysis step performed on the intact biological sample. By simultaneously measuring optical and electrical properties in one operation without requiring sample separation into multiple tubes, the device eliminates time-consuming preparation steps while maintaining measurement accuracy through multi-parameter detection
Solution Approach 2:
The device performs preliminary action by conducting all necessary measurements simultaneously on the original sample before any deterioration can occur. The integrated sensors capture multiple parameters in a single measurement event, eliminating the sequential processing and repeated handling that causes time loss and sample degradation
3Measurement precision
If chemical dosage is used for measurement, then measurement precision is improved, but sample deterioration increases
Solution Approach 1:
The patent replaces chemical dosage methods with physical measurement techniques. Optical sensors detect absorbance and fluorescence properties, while electroanalytical sensors measure electrical conductivity and impedance. These physical methods provide accurate biomarker concentration measurements without introducing chemicals that could alter or deteriorate the sample composition
4Reliability
If results are aggregated from multiple machines, then diagnostic thoroughness is improved, but loss of time increases
Solution Approach 1:
The device merges multiple measurement functions into a single integrated system that simultaneously collects all necessary data. The optical sensors and electroanalytical sensors operate concurrently to gather comprehensive measurement data in one operation, eliminating the time required to aggregate results from multiple separate machines while maintaining diagnostic reliability through multi-parameter analysis
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables fast, thorough, and reliable diagnosis by minimizing sample manipulation, reducing errors and enhancing the precision of biomarker detection through combined electrochemical and optical measurements.
Implementation Method 1
a lighting module configured to emit light in said biological sample through the sample container
Implementation Method 2
an optical sensor configured to receive light emitted by said biological sample
Implementation Method 3
an optical sensor configured to receive light transmitted through said biological sample
Implementation Method 4
an optical sensor configured to receive light scattered in said biological sample
Implementation Method 5
at least one electroanalytical sensor
Data Source
AI summary
An analysis device configured to simultaneously measure multiple parameters of a biological sample, the analysis device having: at least one sample container configured to contain a biological sample; and at least one measuring base configured to cooperate with the sample container, wherein the measuring base includes: at least one electroanalytical sensor; a lighting module configured to emit light in the biological sample through the sample container; and an optical sensor configured to receive light emitted by the biological sample, light transmitted through the biological sample and/or light scattered in the biological sample; wherein the sample container and the measuring base include a mutual cooperation element. Also, a method of analysis of a biological sample implemented by the analysis device.