Bioanalytical Cartridge Platform Dynamics for Interface Protection
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Solution Overview
Problem
Existing bioanalytical reaction devices face issues with interface damage and contamination due to handling, which can lead to leakage and false optical detection results.
Innovation Solution
A cartridge design with a movable platform that protects the sample chamber interface, allowing it to be extended for processing and analysis while maintaining a stowed position to prevent damage and contamination, incorporating a channel for fluid connection and integration with actuation means for mechanical and fluid connections.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Use of energy by moving object
If the interface wall is made thin to enable effective heating and optical detection, then the heating efficiency and optical transparency are improved, but the interface becomes susceptible to damage and contamination from handling
Solution Approach 1:
The platform is designed to be movable between a stowed position (where the interface is protected inside the housing) and an extended position (where the interface is accessible for heating and optical detection). This dynamic configuration allows the thin interface wall to remain protected during handling while being exposed only when needed for its function.
Solution Approach 2:
The movable platform acts as an intermediary between the thin interface wall and the external environment. By controlling the platform's position, the system mediates between the need for an exposed interface (for heating and detection) and the need to protect it from damage and contamination.
2Measurement precision
If the interface wall is made thin to improve optical transparency for detection, then the optical detection accuracy is improved, but the interface becomes easily contaminated by sweat or grease from finger contact
Solution Approach 1:
The platform moves to extend the interface only when needed for optical detection, minimizing the time the thin interface is exposed to contamination risks during handling. The interface remains protected inside the housing during storage and transport.
Solution Approach 2:
The housing structure provides preliminary protection against contamination by enclosing the interface during storage and handling. The interface is only exposed when the platform is extended for controlled optical detection, preventing sweat or grease deposition during normal handling.
3Ease of operation
If the platform is extended to allow access to the interface for processing and analysis, then the bioanalytical processing capability is improved, but the interface becomes vulnerable to damage and contamination
Solution Approach 1:
The platform is designed to be movable between extended and stowed positions, allowing the interface to be accessible only when needed for bioanalytical processing. This dynamic configuration ensures the interface is protected during storage and handling while being easily accessible during operation.
Solution Approach 2:
The system prepares for interface access by extending the platform only when bioanalytical processing is required. This preliminary action of extending the platform on demand ensures the interface is accessible for processing while minimizing exposure time to potential damage or contamination.
Data Source
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AI summary
This invention relates to apparatus for performing bioanalytic processing and analysis. In particular, the present invention relates to a bioanalytical reaction device and a cartridge thereof. The cartridge (10) contains at least one sample chamber (34) in a platform (30) for storing biological samples, the bioanalytical reaction device can process and analyze. The platform is movably connected to a housing, such that the platform is movable by actuating an actuation means between a stowed position, in which the sample chamber is protected by the housing, and an extended position, in which the sample chamber is outside of the housing.