Biochemical Carriers With Index Codes For High Density Data Storage
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Solution Overview
Problem
Current methods for storing and handling biochemical molecules, such as nucleic acids and proteins, are inefficient in terms of space utilization and integration, as they require large containers for indexing and storage, and existing digital data storage formats cannot preserve the original form of biochemical substances during analysis and reuse.
Innovation Solution
Biochemical carriers are developed, comprising encoded biochemical molecules connected to a porous polymer matrix with an index code, allowing for high integration and stability of data storage, where the molecules are immobilized within the matrix and protected by a durable inorganic layer, enabling easy indexing, handling, and repeated use without data loss.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If biochemical molecules are stored in large containers with indexes on the surface, then the molecules can be identified and handled, but the space utilization efficiency deteriorates
Solution Approach 1:
The patent embeds the index code directly within the biochemical molecules themselves, nesting the identification information inside the storage medium rather than placing it externally on containers. This allows the molecules to serve dual purposes: both as the data storage medium and as the indexed identifier, eliminating the need for separate container indexing infrastructure.
Solution Approach 2:
The patent transitions from two-dimensional surface indexing on external containers to three-dimensional integration within the molecular structure itself. By encoding indexes within the molecular sequences and incorporating them into the polymer matrix, the system utilizes the internal dimension of the storage medium rather than relying on external surface area.
2Quantity of substance
If biochemical molecules are dried or mixed in buffer for storage, then they can be stored in containers, but the molecules lose individual distinction and integration efficiency deteriorates
Solution Approach 1:
The patent segments the biochemical molecules into individual carrier particles, each containing a specific set of molecules with unique index codes. This segmentation maintains individuality by ensuring each particle is distinct and identifiable, while still allowing efficient storage of multiple molecules within each particle's capacity.
Solution Approach 2:
The patent applies local quality by incorporating index codes specifically into the polymer matrix surrounding each biochemical molecule or group of molecules. This localized indexing approach preserves the individual identity and properties of each molecular carrier while enabling unified storage and handling, avoiding the homogenization that occurs when molecules are mixed in buffer.
3Loss of information
If conventional digital data storage methods are used for biochemical molecules, then data can be stored, but the original form of biochemical substances cannot be preserved during analysis and reuse
Solution Approach 1:
The patent creates a physical copy of the biochemical molecules within the polymer matrix carrier particles, where the molecules are immobilized in a stable state that preserves their original form and sequence information. This physical copying approach allows repeated analysis and reuse without degrading the molecular integrity, unlike conventional digital storage that loses physical substance.
Solution Approach 2:
The patent uses composite materials by combining biochemical molecules with a polymer matrix to create carrier particles that maintain both the data storage function and the molecular integrity. The polymer matrix provides a stable, protective environment that preserves the biochemical molecules' original form and properties, enabling repeated use without degradation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The biochemical carriers achieve high storage density and stability, allowing for efficient indexing, handling, and repeated use of biochemical molecules, transforming conventional digital data storage into a write-once-read-many (WORM) system with enhanced data preservation and retrieval capabilities.
Implementation Method 1
curing the mixture to obtain carrier particles including a polymer matrix
Data Source
AI summary
Biochemical carriers are provided. Each of the biochemical carriers includes: biochemical molecules having a sequence into which digital data information is encoded; a carrier particle composed of a polymer matrix and in which the biochemical molecules are connected to the surface or inside of the polymer matrix; and an index code introduced into the carrier particle. Also provided is a method for fabricating biochemical carriers. The fabrication method includes: encoding digital data into a sequence of biochemical molecules; synthesizing the biochemical molecules based on the encoded sequence; mixing the biochemical molecules with a photocurable material; curing the mixture to obtain carrier particles including a polymer matrix; and introducing an index code into the carrier particles simultaneously with or separately from the curing. Also provided is a method for restoring digital data from the biochemical carrier. The restoration method includes: analyzing the index code of the biochemical carrier; reacquiring the biochemical molecules from the biochemical carrier based on the analytical results of the index code; sequencing the biochemical molecules; and decoding the sequencing results to restore digital data.