Biochemical Scaffold Harmonic Oscillation for Menopausal Symptom Relief
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Solution Overview
Problem
Current treatments for menopausal symptoms, particularly hot flashes, such as hormone replacement therapy and non-hormonal compositions like fezolinetant, are associated with significant side effects and health risks, necessitating the development of alternative biochemical scaffolds that can effectively reduce and abate hot flashes without these drawbacks.
Innovation Solution
The use of biochemical scaffolds comprising a liquid medium with modulators of the Krebs cycle, neurotransmitters, nuclear hormone receptors, glutathione, DNA, and the endocannabinoid system, subjected to harmonic oscillation, to induce and modulate molecular and cellular activities, thereby reducing hot flash frequency and intensity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If hormone replacement therapy is used to treat menopausal symptoms, then hot flash frequency and intensity are reduced, but the risk of developing cancers, heart attack, and strokes increases
Solution Approach 1:
The patent introduces biochemical scaffolds as intermediary substances that modulate molecular and cellular activities to treat hot flashes without using traditional hormones. These scaffolds act as mediators between the body's natural biochemical processes and the therapeutic effect, achieving symptom relief while avoiding the harmful side effects of hormone replacement therapy.
Solution Approach 2:
The patent changes the biochemical parameters of the treatment by using compositions with specific molecular weights, concentrations, and biochemical pathways (Krebs cycle modulators, neurotransmitter modulators, nuclear hormone receptor modulators) instead of traditional hormonal parameters. This parameter transformation allows treatment of hot flashes through alternative biochemical mechanisms that do not carry the same cardiovascular and cancer risks.
2Object-generated harmful factors
If non-hormonal compositions like fezolinetant are used to treat hot flashes, then hormonal side effects are avoided, but significant side effects such as abdominal disorders, diarrhea, and insomnia occur
Solution Approach 1:
The patent creates a multi-functional treatment composition that simultaneously addresses multiple menopausal symptoms through a single biochemical scaffold system. The composition includes modulators for Krebs cycle, neurotransmitters, nuclear hormone receptors, glutathione, DNA, and endocannabinoid system, providing universal treatment for hot flashes and other menopausal symptoms without the side effect profile of single-target drugs like fezolinetant.
Solution Approach 2:
The patent uses composite biochemical scaffolds that combine multiple bioactive components in a single composition. These composite materials include various modulators working synergistically to treat menopausal symptoms, replacing the single-component approach of fezolinetant with a multi-component system that achieves broader therapeutic effects with fewer side effects.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The biochemical scaffolds significantly reduce the occurrence and intensity of hot flashes by enhancing molecular and cellular activities, providing a safer alternative to existing treatments by minimizing side effects and health risks.
Implementation Method 1
The biochemical scaffold is subjected to harmonic oscillation to induce and modulate molecular and cellular activities
Data Source
AI summary
Biochemical scaffolds for treating menopausal symptoms. The biochemical scaffolds include a base liquid medium, a bioenergetic platform and a vibrational platform. The bioenergetic platform includes at least one Krebs cycle modulator and/or neurotransmitter modulator and/or nuclear hormone receptor modulator. The vibrational platform includes at least one energy signature component, e.g., an herb. The biochemical scaffold is subjected to sequential harmonic oscillation for a defined, predetermined period of time, wherein the energy signature of the energy signature component is imparted to, captured, replicated, and retained by the liquid medium, and, when the biochemical scaffolds are delivered to and, thus, in communication with biological tissue, the biochemical scaffolds induce specific biochemical activities via the resonant transfer of the retained energy signature to the biological tissue and, hence, endogenous cells thereof.