Biochemical Test Module with Perforated Structure
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Solution Overview
Problem
Conventional biochemical test modules face challenges in manufacturing complexity and cost due to the need for dual reaction zones on the same substrate, which can lead to inaccurate measurements due to interference between the samples.
Innovation Solution
The biochemical test module comprises a first and a second reaction piece, each with a substrate, separator, and cover, featuring a perforated structure that separates from the flow channel and hole, allowing independent measurement without interference and enabling observation and ventilation of the second reaction piece.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If two reaction zones are formed on the same substrate to enable multiple measurements, then the quantity of tests increases, but the measurement precision deteriorates due to current interference between samples
Solution Approach 1:
The patent divides the test system into separate reaction pieces (first reaction piece and second reaction piece), each with its own substrate, separator, and cover forming independent reaction zones. This segmentation eliminates current interference between samples while maintaining the capability for multiple simultaneous measurements, thus resolving the contradiction between increased test quantity and maintained measurement precision.
2Productivity
If two reaction zones are formed on the same substrate to enable multiple measurements, then the quantity of tests increases, but the device complexity increases due to manufacturing difficulties
Solution Approach 1:
Instead of creating complex dual reaction zones on a single substrate, the patent segments the system into multiple independent reaction pieces that can be manufactured separately using standard single-substrate processes, then assembled together. This approach maintains manufacturing simplicity while achieving multi-test functionality.
Solution Approach 2:
The patent employs a nested structure where multiple reaction pieces are stacked and connected vertically. The first reaction piece and second reaction piece are arranged in layers, with sampling ports and flow channels connected through the stack. This nesting approach enables multiple tests within a compact form factor while keeping each individual reaction piece relatively simple to manufacture.
3Ease of operation
If a single sampling port is used to enter samples into two reaction zones, then the ease of operation improves, but the reliability deteriorates due to potential cross-contamination and interference
Solution Approach 1:
The patent provides for separate sampling ports (first sampling port and second sampling port) for each reaction piece, eliminating the risk of cross-contamination and current interference that would occur with a shared sampling port. Each reaction piece can be operated independently, maintaining reliability while still allowing sequential or simultaneous testing.
Data Source
AI summary
The present disclosure provides a biochemical test module. The biochemical test module includes a first reaction piece and a second reaction piece. The first reaction piece includes a first substrate; a first separator located on the first substrate and having a first flow channel exposing at least a portion of the first substrate; and a first cover covering the first separator. The first hole is connected with a first channel. The first reaction piece has a perforated structure penetrating the first cover, the first separator and the first substrate. The second reaction piece is disposed on one side of the first reaction piece adjacent to the first substrate and includes a second substrate; a second separator located on the second substrate and having a second flow channel exposing at least a portion of the second substrate; and a second cover covering the second separator and joined to the first substrate.