Biochip Pillar Structure with Smooth Substrate Grooves

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Solution Overview

Problem

The existing biochip pillar structures suffer from image distortion and reduced optical precision due to concave grooves on the substrate surface, leading to light refraction and increased risk of surface scratches when biochips are stacked.

Innovation Solution

A biochip pillar structure with smooth surface forming portions on the substrate surface, forming flat and smooth cylindrical grooves around the pillar portions to prevent light refraction and scratches, enhancing optical precision and measurement reliability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the substrate portion is made flat and smooth to prevent scratches during stacking, then the reliability of sample protection is improved, but the injection molding process becomes more difficult due to the need for additional smooth surface forming portions

Engineering Contradiction:
Improvescratch prevention reliabilityVSAvoidinjection molding difficulty
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The substrate portion is segmented into functional zones: a flat smooth surface area for scratch prevention during stacking, and a recessed groove area for pillar formation. This segmentation allows the mold to create distinct regions with different surface properties, enabling both scratch protection and proper pillar formation through injection molding by using a mold with corresponding segmented cavity structures

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different surface qualities are applied to different regions of the substrate portion. The flat smooth surface forming portion provides a scratch-resistant surface for stacking, while the groove forming portion provides the necessary texture and structure for pillar formation. This local quality differentiation resolves the contradiction by ensuring each region has the optimal surface properties for its specific function

Inventive Principle:
Principle #3Local quality

2Manufacturing precision

If grooves are formed in the substrate portion to support pillar structures, then the manufacturing precision of pillar positioning is improved, but light refraction occurs causing image distortion that reduces measurement precision

Engineering Contradiction:
Improvepillar positioning precisionVSAvoidoptical measurement precision
Core Design Contradiction:
Manufacturing precisionVSMeasurement precision

Solution Approach 1:

The solution moves the optical measurement function to a different dimension by using the side surface of the pillar portion rather than looking through the substrate. The groove structure supports the pillar vertically, while optical measurement is performed laterally through the pillar side, eliminating light refraction through the substrate while maintaining precise pillar positioning through the groove structure

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The pillar portion acts as an intermediary structure that connects the groove-based positioning system with the optical measurement system. The groove provides precise positioning, the pillar transmits this positioning accuracy, and the pillar side surface enables optical measurement without requiring the light to pass through the grooved substrate portion

Inventive Principle:
Principle #24Intermediary (Mediator)

3Strength

If the pillar portion thickness is increased to improve structural strength, then the strength of the pillar is improved, but light loss increases due to increased absorption and refraction

Engineering Contradiction:
Improvepillar structural strengthVSAvoidlight loss
Core Design Contradiction:
StrengthVSLoss of energy

Solution Approach 1:

The solution replaces the traditional approach of increasing pillar thickness for strength with a groove-based support system in the substrate. The groove structure provides mechanical support and positioning stability, allowing the pillar to maintain optimal thickness for light transmission while deriving structural strength from the groove constraints rather than pillar bulk

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The smooth surface forming portions effectively prevent image distortion and scratches, improving measurement reliability and optical precision by allowing unobstructed light penetration and reducing surface damage during biochip stacking.

Implementation Method 1

the biochip enables the sample to be measured by a microscope through the pillar portion 12 through which light penetrates

Methodology Applied
Scientific EffectLight penetration: Light

Implementation Method 2

the smooth surface forming portions forming flat and smooth surfaces... such that the cylindrical groove shape is formed... effectively prevent image distortion... by allowing unobstructed light penetration

Methodology Applied
Scientific EffectLight refraction prevention: Refraction

Data Source

PatentEP3608020B1Pillar structure for bio-chip
Publication Date: 2023.11.29 MBD CO LTD
  • EP3608020B1 patent drawingFigure 1
  • EP3608020B1 patent drawingFigure 2
  • EP3608020B1 patent drawingFigure 3

AI summary

The present invention relates to a pillar structure for a biochip, the pillar structure including: a substrate portion which has a plate-shaped structure; multiple pillar portions which protrude from one surface of the substrate portion and each of which has an end portion on which a sample is disposed; and smooth surface forming portions which are formed on the other surface of the substrate portion that defines the plate-shaped structure together with the one surface of the substrate portion, the smooth surface forming portions forming smooth surfaces each having a relatively concave groove shape at a portion corresponding to a circumferential surface of each of the pillar portions.