Biocompatible Solid Electrode for Nerve Stimulators

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Solution Overview

Problem

Conventional nerve stimulator electrodes cause immune responses and physical damage due to their mechanical properties and electrochemical reactions with biological tissues, leading to instability and side effects during long-term use.

Innovation Solution

A biocompatible solid electrolyte nerve stimulator electrode with an ion diffusion barrier, composed of an ionic liquid and a biocompatible polymer matrix, is developed to mimic mechanical properties of living tissue, prevent ion exchange reactions, and utilize a capacitive charge injection mechanism to avoid direct charge transfer and electrochemical damage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Power

If conventional metal or silicon materials are used for nerve electrodes, then electrical stimulation can be delivered, but mechanical damage and immune response occur due to high mechanical modulus

Engineering Contradiction:
Improveelectrical stimulation deliveryVSAvoidmechanical damage and immune response
Core Design Contradiction:
PowerVSObject-affected harmful factors

Solution Approach 1:

The patent changes the mechanical parameter (modulus) of the electrode material from high (metal/silicon) to low (soft material with modulus close to living tissue). This parameter change allows the electrode to deliver electrical stimulation while avoiding mechanical damage and immune response by matching the mechanical properties of the surrounding tissue.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses composite materials consisting of soft material substrate combined with conductive material. This composite structure provides both the mechanical compliance of soft materials (to avoid damage) and the electrical conductivity needed for stimulation delivery, resolving the contradiction between mechanical safety and electrical functionality.

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If conductive polymer materials are used to make electrodes thin and flexible, then mechanical damage is reduced, but hydrogen ions and gas are generated during oxidation/reduction reactions causing pressure on nerves

Engineering Contradiction:
Improvemechanical damageVSAvoidhydrogen ions and gas generation
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The patent extracts and eliminates the electrochemical reaction mechanism (oxidation/reduction) that causes harmful hydrogen ion and gas generation. By using ionic conduction instead of electron conduction with electrochemical reactions, the harmful byproducts are removed while maintaining the ability to deliver electrical stimulation.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent substitutes the electrochemical charge injection mechanism with an ionic conduction mechanism. Instead of using electron transfer through oxidation/reduction reactions, the system uses ion movement through the soft material to deliver charge, eliminating the generation of harmful chemical byproducts.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Object-affected harmful factors

If metal materials are made thin and formed on flexible polymer substrates, then mechanical compatibility improves, but electrochemical reactions still cause immune response

Engineering Contradiction:
Improvemechanical compatibilityVSAvoidimmune response from electrochemical reactions
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The patent substitutes electrochemical charge injection with ionic conduction through soft materials. This replacement eliminates the electrochemical reactions at the electrode-tissue interface that cause immune responses, while maintaining mechanical compatibility through the use of soft material substrates.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the charge injection mechanism from electrochemical (electron transfer) to ionic conduction. This parameter change in the electrical delivery mechanism eliminates harmful electrochemical reactions while preserving the ability to deliver effective neural stimulation.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The electrode maintains a stable nervous system during body movement, suppresses ion exchange reactions, and prevents side effects by using a capacitive charge injection mechanism, allowing for long-term use without immune responses or physical damage.

Implementation Method 1

the biocompatible solid electrolyte may allow ion movement and form an electric double layer under an electric field

Methodology Applied
Scientific EffectIon movement: Electrolyte

Implementation Method 2

form an electric double layer under an electric field

Methodology Applied
Scientific EffectElectric double layer formation: Capacitance

Implementation Method 3

an ion diffusion barrier is formed on the biocompatible solid electrolyte

Methodology Applied
Scientific EffectIon diffusion barrier: Diffusion Barrier

Data Source

PatentUS20240238586A1Electrode for nerve stimulator comprising biocompatible solid electrolyte, method for manufacturing same, and nerve stimulator comprising same
Publication Date: 2024.07.18 INDUSTRY UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
  • US20240238586A1 patent drawing
  • US20240238586A1 patent drawing
  • US20240238586A1 patent drawing

AI summary

Disclosed are a nerve stimulator electrode and a method of manufacturing the same. More particularly, the present invention provides a nerve stimulator electrode including biocompatible solid electrolyte; and an ion diffusion barrier formed on the biocompatible solid electrolyte, wherein the biocompatible solid electrolyte includes an ionic liquid and a biocompatible polymer matrix.