Biocompatible Titanium Alloy for Additive Manufacturing

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Solution Overview

Problem

Current titanium-based alloys for biomedical applications have limitations in additive manufacturability, biocompatibility, and microstructure stability, with traditional compositions often requiring costly and time-consuming experimental development and containing elements with adverse health effects.

Innovation Solution

A titanium-based alloy composition with specific ranges of niobium, molybdenum, tantalum, zirconium, and tin is developed, optimized using the 'Alloys-By-Design' method to enhance biocompatibility, manufacturability, and mechanical performance, while minimizing toxic elements and improving microstructural stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If traditional titanium-based alloys are used for biomedical applications, then mechanical strength is achieved, but additive manufacturability deteriorates due to cracking susceptibility and microstructure instability

Engineering Contradiction:
Improveadditive manufacturabilityVSAvoidmicrostructure stability
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent applies parameter changes by systematically adjusting the chemical composition parameters of the titanium alloy, specifically limiting Al to 0.5-6.0 wt%, V to 0.5-5.0 wt%, Fe to 0.5-3.0 wt%, and incorporating specific amounts of Mo, Nb, Ta, Zr, and Sn to achieve optimal microstructure stability and additive manufacturability

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite alloy system by combining multiple alloying elements (Mo, Nb, Ta, Zr, Sn) with titanium base, where each element contributes specific properties: Mo and Nb for beta-phase stabilization and grain refinement, Ta for high-temperature strength, Zr for biocompatibility, and Sn for corrosion resistance, achieving synergistic effects that resolve the contradiction between manufacturability and reliability

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If traditional alloy compositions are used, then mechanical performance is achieved, but biocompatibility deteriorates due to presence of toxic elements

Engineering Contradiction:
ImprovebiocompatibilityVSAvoidmechanical strength
Core Design Contradiction:
Object-affected harmful factorsVSStrength

Solution Approach 1:

The patent applies the extraction principle by removing or severely limiting toxic elements (Al to 0.5-6.0 wt%, V to 0.5-5.0 wt%, Fe to 0.5-3.0 wt%) from the alloy composition that are known to have adverse health effects, while maintaining mechanical strength through substitution with biocompatible alternative elements

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the compositional parameters by introducing biocompatible elements (Mo: 2.0-10.0 wt%, Nb: 5.0-15.0 wt%, Ta: 2.0-10.0 wt%, Zr: 2.0-10.0 wt%, Sn: 2.0-10.0 wt%) that have proven non-toxic and bone-friendly properties, thereby improving biocompatibility while preserving mechanical performance

Inventive Principle:
Principle #35Parameter changes

3Strength

If alloying elements are added to improve mechanical properties, then strength increases, but manufacturing complexity increases due to solidification range expansion

Engineering Contradiction:
Improvemechanical strengthVSAvoidsolidification behavior complexity
Core Design Contradiction:
StrengthVSDevice complexity

Solution Approach 1:

The patent applies local quality by assigning specific functional roles to different alloying elements: Mo and Nb primarily for grain refinement and beta-phase stabilization, Ta for high-temperature strength, Zr for biocompatibility, and Sn for corrosion resistance, with each element added in controlled amounts (2.0-10.0 wt% range) to achieve targeted local improvements without excessive overall complexity

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent optimizes the concentration parameters of alloying elements within specific ranges (Mo: 2.0-10.0 wt%, Nb: 5.0-15.0 wt%, Ta: 2.0-10.0 wt%, Zr: 2.0-10.0 wt%, Sn: 2.0-10.0 wt%) to balance strength enhancement with manageable solidification behavior, avoiding excessive alloying that would expand the solidification range and complicate manufacturing

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP3759258B1A bio-compatible titanium alloy optimised for additive manufacturing
Publication Date: 2022.04.13 ALLOYED LTD
  • EP3759258B1 patent drawingFigure 1
  • EP3759258B1 patent drawingFigure 2
  • EP3759258B1 patent drawingFigure 3

AI summary

A titanium-based alloy composition consisting in weight percent, of: between 15.0 and 35.0 % niobium, between 0.0 and 7.5 % molybdenum, between 0.0 and 20.0% tantalum, between 0 and 7.0% zirconium, between 0 and 6.0% tin, between 0.0 and 2.0% hafnium, between 0.0 and 0.5 % aluminium, between 0.0 and 0.5 % vanadium, between 0.0 and 0.5 % iron, between 0.0 and 0.5 % chromium, between 0.0 and 0.5% cobalt, between 0.0 and 0.5 % nickel, between 0.0 and 1.0% silicon, between 0.0 and 0.2% boron, between 0.0 and 0.5% calcium, between 0.0 and 0.5% carbon, between 0.0 and 0.5% manganese, between 0.0 and 0.5% gold, between 0.0 and 0.5% silver, between 0.0 and 0.5% oxygen, between 0.0 and 0.5% hydrogen, between 0.0 and 0.5% nitrogen, between 0.0 and 0.5% palladium, between 0.0 and 0.5% lanthanum, the balance being titanium and incidental impurities, wherein the composition satisfies the following equation: 0.0175Nb + 0.0183Mo + 0.03Ta + 0.0116Zr + 0.1Sn > 1.0 where Nb, Mo, Ta, Zr and Sn represent the amounts of niobium, molybdenum, tantalum, zirconium and tin in wt% respectively.