Biocomposite Medical Implants with High Mineral Content

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Solution Overview

Problem

Current medical implants, particularly those made from metals and biostable polymers, face challenges such as the need for secondary surgeries for removal, mechanical failure due to fatigue, and inadequate mechanical properties for load-bearing applications, leading to complications like peri-prosthetic fractures and inflammatory responses.

Innovation Solution

Development of biocomposite materials with high mineral content, specifically using mineral fibers reinforced in a polymer matrix, which provide superior mechanical properties and are bioabsorbable, maintaining strength and stiffness equivalent to or exceeding cortical bone for extended periods.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If metal implants are used for load-bearing orthopedic applications, then high strength and stiffness are achieved, but the need for secondary surgery for removal increases and stress shielding occurs

Engineering Contradiction:
ImprovestrengthVSAvoidstress shielding
Core Design Contradiction:
StrengthVSObject-generated harmful factors

Solution Approach 1:

The patent changes the material parameters by using biodegradable polymers with controlled degradation rates instead of permanent metals. The implant's mechanical properties evolve over time as it degrades, transitioning from high strength initially to complete resorption, thereby eliminating stress shielding while maintaining adequate support during healing

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs biodegradable materials that are intentionally designed to be discarded by the body's natural metabolic processes. The implant degrades into non-toxic byproducts that are absorbed or excreted, eliminating the need for secondary removal surgery while the material gradually transfers load to the healing bone

Inventive Principle:
Principle #34Discarding and recovering

2Object-generated harmful factors

If biodegradable polymer implants are used to eliminate secondary surgery, then the need for removal surgery is eliminated, but mechanical strength and stiffness are insufficient for load-bearing applications

Engineering Contradiction:
Improveneed for removal surgeryVSAvoidmechanical strength
Core Design Contradiction:
Object-generated harmful factorsVSStrength

Solution Approach 1:

The patent creates composite structures by combining biodegradable polymer matrices with reinforcing elements such as glass fibers, metal fibers, or ceramic particles. This composite approach enables the implant to achieve high initial mechanical strength equivalent to cortical bone while maintaining the biodegradable property that eliminates removal surgery

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent modifies the polymer's mechanical parameters through crosslinking, blending, or molecular weight control to enhance strength and stiffness. Simultaneously, the degradation rate is tuned to match bone healing timelines, ensuring adequate mechanical support is maintained throughout the critical healing period

Inventive Principle:
Principle #35Parameter changes

3Duration of action of stationary object

If biodegradable polymer implants are used, then eventual resorption occurs eliminating removal surgery, but mechanical properties become insufficient after repeated dynamic loading

Engineering Contradiction:
Improveresorption timeVSAvoidmechanical reliability
Core Design Contradiction:
Duration of action of stationary objectVSReliability

Solution Approach 1:

The patent adjusts the degradation kinetics by modifying polymer composition, crystallinity, and molecular structure to ensure the material maintains mechanical integrity throughout the required service period. The degradation rate is controlled to prevent premature strength loss while ensuring complete resorption within an acceptable timeframe

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent incorporates reinforcement phases with different degradation rates than the polymer matrix. These reinforcements (such as glass fibers or ceramic particles) maintain structural integrity longer, providing mechanical reliability under dynamic loading conditions while the polymer gradually degrades

Inventive Principle:
Principle #40Composite materials

Data Source

PatentEP3474913B1Fiber reinforced biocomposite medical implants with high mineral content
Publication Date: 2024.05.08 OSSIO LTD
  • EP3474913B1 patent drawingFigure 1
  • EP3474913B1 patent drawingFigure 2
  • EP3474913B1 patent drawingFigure 3

AI summary

A medical implant comprising a plurality of layers, each layer comprising a polymer and a plurality of uni-directionally aligned continuous reinforcement fibers.