Biodegradable Amber Odorant Compounds for Ambergris-Like Notes

Solution Overview

Problem

There is a need for a less expensive synthetic alternative to natural ambergris that imparts woody and amber odor notes with low volatility, while being biodegradable and environmentally friendly, to replace rare and costly natural ambergris used in perfumery.

Innovation Solution

Development of biodegradable compounds of formula (I) that impart a powerful woody and amber note, which can be used as perfuming ingredients in perfuming compositions and perfumed consumer products, enhancing or modifying odor properties by adding an effective amount of these compounds to perfuming compositions or articles.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If synthetic alternatives to natural ambergris are developed to reduce cost and increase availability, then cost and accessibility are improved, but biodegradability and environmental friendliness deteriorate

Engineering Contradiction:
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent modifies the molecular structure of synthetic ambergris alternatives by introducing biodegradable functional groups and adjusting chemical parameters to achieve both synthetic availability and environmental compatibility. The compounds of formula (I) represent a parameter change from non-biodegradable synthetics to biodegradable synthetics while maintaining the desired ambergris odor profile.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If synthetic compounds are designed to mimic natural ambergris odor, then odor similarity is improved, but biodegradability deteriorates

Engineering Contradiction:
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent applies local quality by maintaining the core molecular structure responsible for ambergris odor while modifying specific regions of the molecule to introduce biodegradable characteristics. The compounds of formula (I) preserve the essential odor-generating structural features while incorporating biodegradable elements at specific locations in the molecular structure.

Inventive Principle:
Principle #3Local quality

3Measurement precision

If prior art synthetic compounds are used to achieve ambergris notes, then odor properties are improved, but biodegradability and environmental compatibility worsen

Engineering Contradiction:
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent creates composite molecular structures that combine the odor-generating core of traditional ambergris synthetics with biodegradable functional groups. The compounds of formula (I) represent a composite approach, merging the essential ambergris odor profile with environmentally friendly biodegradable characteristics to achieve both organoleptic quality and ecological compatibility.

Inventive Principle:
Principle #40Composite materials

Data Source

PatentEP3883927B1Amber odorant
Publication Date: 2025.10.01
  • EP3883927B1 patent drawingFigure 1
  • EP3883927B1 patent drawing
  • EP3883927B1 patent drawing

AI summary

The present invention concerns compound of formula (I) in the form of any one of its stereoisomers or as a mixture thereof, and wherein R1 represents a hydrogen atom, a C1-3 alkyl group or C2-3 alkenyl group; X represents an oxygen atom when R2 represents a C1-4 alkyl group or C2-4 alkenyl group or X represents a CH2-O group when R2 represents a C2-4 alkenyl group or a MeC=O group. The use as a perfuming ingredient of the invention's compound and the invention's compound as part of a perfuming composition or of a perfuming consumer product are also part of the present invention.