Biodegradable Carrier for Needle-Free Injection Kinetic Energy

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Solution Overview

Problem

Needle-based injection devices cause pain, infection risk, environmental pollution, and tissue damage due to metal particles that cannot be degraded or metabolized within the target object, hindering the efficacy of active substances.

Innovation Solution

A delivery object for needle-free injection equipment comprising a biodegradable material layer encapsulating an active substance, placed within a delivery object carrier formed by main and cross-linking chains, allowing for kinetic energy acquisition and degradation within the target object, reducing tissue damage and enabling controlled release of the active substance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If metal particles are used as delivery objects, then sufficient kinetic energy can be achieved to penetrate biological tissues, but the metal particles cause superficial damage to cells or biological tissues and cannot be degraded or metabolized within the target object

Engineering Contradiction:

Improvekinetic energyVSAvoidtissue damage

Core Design Contradiction:

SpeedVSObject-affected harmful factors

Solution Approach 1:

The patent changes the material parameter from metal particles to biodegradable polymer particles, which allows the delivery object to maintain sufficient kinetic energy for tissue penetration while enabling degradation and metabolism within the target object, thereby eliminating long-term harm

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent uses biodegradable polymer particles that can be degraded or metabolized within the target object, replacing permanent metal particles. These disposable-like particles provide sufficient kinetic energy during delivery but then disappear through biological degradation, avoiding accumulation and long-term damage

Inventive Principle:

Principle #27Cheap short-living objects (Disposable)

2Speed

If metal particles are used as delivery objects, then sufficient kinetic energy can be achieved to penetrate biological tissues, but the metal particles accumulate in the target object causing harm to the target object

Engineering Contradiction:

Improvekinetic energyVSAvoidaccumulation harm

Core Design Contradiction:

SpeedVSObject-generated harmful factors

Solution Approach 1:

The patent changes the material parameter from non-biodegradable metal particles to biodegradable polymer particles, enabling the delivery object to provide sufficient kinetic energy during penetration and then be completely degraded or metabolized within the target object, preventing accumulation and long-term harm

Inventive Principle:

Principle #35Parameter changes

3Speed

If metal particles are used as delivery objects, then sufficient kinetic energy can be achieved to penetrate biological tissues, but delivery objects made of metal particles have difficulty forming a suspended state within the needle-free injection equipment

Engineering Contradiction:

Improvekinetic energyVSAvoidsuspended state formation

Core Design Contradiction:

SpeedVSDevice complexity

Solution Approach 1:

The patent changes the material parameter from metal particles to biodegradable polymer particles with appropriate size and density characteristics, enabling the delivery objects to form a suspended state within the needle-free injection equipment while still achieving sufficient kinetic energy for tissue penetration

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The biodegradable delivery object carrier and material layer are engulfed, degraded, or metabolized without residue, reducing tissue damage and allowing for controlled release of the active substance, enhancing the efficacy and safety of needle-free injection systems.

Implementation Method 1

The delivery object carrier can be engulfed, degraded, or metabolized in the target object, releasing an active substance within the target object

Methodology Applied

Scientific EffectBiodegradation: Decomposition (biological)

Implementation Method 2

The delivery object located in the needle-based injection device is accelerated by a power source, so that the delivery object has sufficient kinetic energy to penetrate cell membranes, cell walls, biological tissues (e.g., skin tissue), and/or organs

Methodology Applied

Scientific EffectKinetic energy:

Data Source

PatentUS20240398696A1Delivery objects suitable for needle-free injection equipments

Publication Date: 2024.12.05 CHUANG PING-YEN

AI summary

This invention provides a delivery object suitable for a needle-free injection equipment. A biodegradable material layer is used to encapsulate an active substance, forming an initial delivery object. Then, multiple initial delivery objects are placed within a carrier space formed by a delivery object carrier, creating a delivery object. The delivery object is placed within the needle-free injection equipment and accelerated by driving force provided by a power source, so that the delivery object has sufficient kinetic energy to be injected into the target object. The delivery object carrier and the biodegradable material layer will be consumed, decomposed, or metabolized within the target object, while releasing the active substance within the target object. Encapsulating the initial delivery object with the delivery object carrier will facilitate the acceleration of the delivery object so that the delivery object has sufficient kinetic energy to be injected into the target.